Effects of G-quadruplex topology on translational inhibition by tRNA fragments in mammalian and plant systems in vitro

•tRNA fragments that fold into G-quadruplexes inhibit mammalian translation.•Efficiency of inhibition depends on the type of G-quadruplex topology.•G-quadruplex fold of a small RNA is not sufficient to inhibit plant translation. The folding of tRNA fragments (tRFs) into G-quadruplex structures and t...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2017-11, Vol.92, p.148-154
Hauptverfasser:	Jackowiak, Paulina, Hojka-Osinska, Anna, Gasiorek, Katarzyna, Stelmaszczuk, Michal, Gudanis, Dorota, Gdaniec, Zofia, Figlerowicz, Marek
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence G-quadruplex G-Quadruplexes Protein Biosynthesis Rabbits RNA, Plant - chemistry RNA, Plant - genetics RNA, Transfer - chemistry RNA, Transfer - genetics Small regulatory RNA Translational inhibition Triticum - genetics tRNA fragments
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