Emergence of ISAba1 harboring carbapenem-resistant Acinetobacter baumannii isolates in Pakistan

The ISAba1 insertion sequence supports the overexpression of various oxacillinases genes by providing promoter and therefore, confers carbapenem resistance. The study aimed to determine the clonal diversity, genetic attributes of carbapenem resistance and the role of ISAba1 in the expression of oxac...

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Veröffentlicht in:	Future microbiology 2017-11, Vol.12 (14), p.1261-1269
Hauptverfasser:	Khurshid, Mohsin, Rasool, Muhammad Hidayat, Ashfaq, Usman Ali, Aslam, Bilal, Waseem, Muhammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii Acinetobacter baumannii - drug effects Acinetobacter baumannii - genetics Acinetobacter baumannii - immunology Acinetobacter Infections - epidemiology Acinetobacter Infections - microbiology Antibiotics Antigens, Bacterial - genetics Antigens, Bacterial - immunology Antimicrobial agents Antimicrobial resistance beta-Lactam Resistance - genetics beta-Lactamases - genetics Carbapenems Carbapenems - pharmacology Clinical isolates Deoxyribonucleic acid DNA DNA Transposable Elements Drug resistance Genes Genetic diversity Humans Insertion Laboratories Multidrug resistance Pakistan - epidemiology Tertiary Care Centers
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