Chemical Approaches to Modulating Complement-Mediated Diseases

Numerous diseases are driven by chronic inflammation, placing major burdens on our health systems. Controlling inflammation is an important preventative and therapeutic goal. Over 40 “Complement” proteins are produced in blood or on cell surfaces through activation of the Complement protein network...

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Veröffentlicht in:Journal of medicinal chemistry 2018-04, Vol.61 (8), p.3253-3276
Hauptverfasser: Iyer, Abishek, Xu, Weijun, Reid, Robert C, Fairlie, David P
Format: Artikel
Sprache:eng
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