Expanding and reprogramming the genetic code

Nature uses a limited, conservative set of amino acids to synthesize proteins. The ability to genetically encode an expanded set of building blocks with new chemical and physical properties is transforming the study, manipulation and evolution of proteins, and is enabling diverse applications, inclu...

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Veröffentlicht in:	Nature (London) 2017-10, Vol.550 (7674), p.53-60
1. Verfasser:	Chin, Jason W.
Format:	Artikel
Sprache:	eng
Schlagworte:	14 14/35 631/1647/1511 631/337/574 631/45/2783 631/92/552 64 64/60 82/80 Amino acids Amino Acids - chemistry Amino Acids - genetics Amino Acids - metabolism Animals Biochemistry Biological evolution Biopolymers Codon - genetics Directed Molecular Evolution E coli Evolution Genetic code Genetic Code - genetics Genetic engineering Genomes Humanities and Social Sciences Humans Methods multidisciplinary Physical properties Physiological aspects Protein Engineering - methods Protein Engineering - trends Protein Processing, Post-Translational Protein synthesis Proteins Proteins - chemistry Proteins - genetics Proteins - metabolism review-article RNA sequencing Science Suppression, Genetic Synthesis Synthetic Biology - methods Synthetic Biology - trends Transfer RNA Transformations (mathematics)
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