MiR‐132‐3p regulates ADAMTS‐5 expression and promotes chondrogenic differentiation of rat mesenchymal stem cells

Previous study showed that miRNA aberrant expression is involved in chondrogenic differentiation. In this study, we aimed to investigate the effects of miR‐132‐3p on chondrogenic differentiation and the underlying mechanisms. First, quantitative PCR were performed to determine the level of MiR‐132‐3...

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Veröffentlicht in:	Journal of cellular biochemistry 2018-03, Vol.119 (3), p.2579-2587
Hauptverfasser:	Zhou, Xiaozhong, Luo, Dixin, Sun, Hongtao, Qi, Yong, Xu, Wangyang, Jin, Xunjie, Li, Chao, Lin, Zhousheng, Li, Guitao
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration ADAMTS‐5 Aggrecan Biocompatibility Biomedical materials chondrogenic differentiation Collagen (type II) Differentiation Ectopic expression Immunofluorescence Mesenchymal stem cells Mesenchyme miRNA miR‐132‐3p Osteoarthritis rat mesenchymal stem cells Sox9 protein Stem cell transplantation Stem cells Target recognition Western blotting
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