Supercritical fluid-micronized ipratropium bromide for pulmonary drug delivery

Ipratropium bromide (IB) was micronized by means of a CO 2-based aerosol solvent extraction system (ASES) in order to improve the particle shape and size characteristics for use in inhalation therapy. The particle size parameter most relevant to pulmonary delivery is the aerodynamic diameter. In thi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Powder technology 2008-02, Vol.182 (1), p.25-32
Hauptverfasser:	Kim, Yong Ho, Shing, Katherine S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerodynamic diameter Aerosol solvent extraction system Applied sciences Chemical engineering Exact sciences and technology Ipratropium bromide Liquid-liquid extraction Miscellaneous Pulmonary delivery Solid-solid systems Supercritical antisolvent
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!