Assembly of the active center of organophosphorus hydrolase in metal-organic frameworks via rational combination of functional ligands

Assembly of the active center of organophosphorus hydrolase in metal-organic frameworks via rational combination of functional ligands

Different from popular mimics of bimetallic nuclear centers bridged by a hydroxide, a total coordination sphere of the active center of organophosphorus hydrolase was assembled in metal-organic frameworks by rational design and combination of ligands, which resulted in efficient destruction of nerve...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2017, Vol.53 (82), p.11302-11305
Hauptverfasser: Xia, Mengfan, Zhuo, Caixia, Ma, Xuejuan, Zhang, Xiaohong, Sun, Huaming, Zhai, Quanguo, Zhang, Yaodong
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container_title Chemical communications (Cambridge, England)
container_volume 53
creator Xia, Mengfan
Zhuo, Caixia
Ma, Xuejuan
Zhang, Xiaohong
Sun, Huaming
Zhai, Quanguo
Zhang, Yaodong
description Different from popular mimics of bimetallic nuclear centers bridged by a hydroxide, a total coordination sphere of the active center of organophosphorus hydrolase was assembled in metal-organic frameworks by rational design and combination of ligands, which resulted in efficient destruction of nerve agent stimulants without a base as a co-catalyst.
doi_str_mv 10.1039/c7cc06270b
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title Assembly of the active center of organophosphorus hydrolase in metal-organic frameworks via rational combination of functional ligands
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