Trio's Rho-specific GEF domain is the missing G alpha sub(q) effector in C. elegans

The G alpha sub(q) pathway is essential for animal life and is a central pathway for driving locomotion, egg laying, and growth in Caenorhabditis elegans, where it exerts its effects through EGL-8 (phospholipase C beta [PLC beta ]) and at least one other effector. To find the missing effector, we pe...

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Veröffentlicht in:	Genes & development 2007-11, Vol.21 (21), p.2731-2746
Hauptverfasser:	Williams, Stacey L, Lutz, Susanne, Charlie, Nicole K, Vettel, Christiane, Ailion, Michael, Coco, Cassandra, Tesmer, John JG, Jorgensen, Erik M, Wieland, Thomas, Miller, Kenneth G
Format:	Artikel
Sprache:	eng
Schlagworte:	Caenorhabditis elegans
Online-Zugang:	Volltext
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