Postoperative Outcomes, Weight Loss Predictors, and Late Gastrointestinal Symptoms Following Laparoscopic Sleeve Gastrectomy
Objective To evaluate the outcomes, weight loss predictors, and gastrointestinal symptoms of patients after laparoscopic sleeve gastrectomy (LSG). Methods The postoperative medical status of the patients was obtained retrospectively using a questionnaire and was compared to existing medical data bef...
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| Veröffentlicht in: | Journal of gastrointestinal surgery 2017-12, Vol.21 (12), p.2009-2015 |
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| container_issue | 12 |
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| container_title | Journal of gastrointestinal surgery |
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| creator | Goldenshluger, Michael Goldenshluger, Ariela Keinan-Boker, Lital Cohen, Matan Joel Ben-Porat, Tair Gerasi, Heba Amun, Majd Abu-Gazala, Mahmud Khalaileh, Abed Mintz, Yoav Elazary, Ram |
| description | Objective
To evaluate the outcomes, weight loss predictors, and gastrointestinal symptoms of patients after laparoscopic sleeve gastrectomy (LSG).
Methods
The postoperative medical status of the patients was obtained retrospectively using a questionnaire and was compared to existing medical data before the surgery.
Results
We included 201 candidates, 178 patients completed mean of 3 years of follow-up. Mean excess body weight loss (%EWL) was 65.14% ± 15.74 at 6 months, 78.53% ± 20.28 at 12 months, and 74.32% ± 23.92 at 3 years after LSG. Older age (
P
= 0.018), higher baseline BMI (
P
= 0.003), and higher number of medications (
P
|
| doi_str_mv | 10.1007/s11605-017-3585-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1946428970</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1946428970</sourcerecordid><originalsourceid>FETCH-LOGICAL-c438t-5a8cf0a62323f42d091abf3d88a94923b0fa3ee711f8b22bc4087fd6b6c46cc03</originalsourceid><addsrcrecordid>eNp1kU1rFTEYhYMo9kN_gBsJuHHRsfmaTLKUYqtwoYUquguZzDvXlJnJmGRaLvjjm-FeRYSuEpLnnOS8B6E3lHyghDTniVJJ6orQpuK1qiv9DB1T1fBKSCaflz3RtGJ1_eMInaR0RwpIqHqJjpjSDWWaHqPfNyHlMEO02d8Dvl6yCyOkM_wd_PZnxpuQEr6J0HmXQyzndurwxmbAVzblGPyUIWU_2QHf7sY5hzHhyzAM4cFP2wLONobkwuwdvh0A7g86KG7j7hV60dshwevDeoq-XX76evG52lxffbn4uKmc4CpXtVWuJ1YyzngvWFdS2bbnnVJWC814S3rLARpKe9Uy1jpBVNN3spVOSOcIP0Xv975zDL-W8l8z-uRgGOwEYUmGaiHFOpMVffcfeheWWOKtlJSKaKJEoeieciVditCbOfrRxp2hxKzVmH01pkzcrNUYXTRvD85LO0L3V_GniwKwPZDK1bSF-M_TT7o-Aj0rm4U</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1966809084</pqid></control><display><type>article</type><title>Postoperative Outcomes, Weight Loss Predictors, and Late Gastrointestinal Symptoms Following Laparoscopic Sleeve Gastrectomy</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Goldenshluger, Michael ; Goldenshluger, Ariela ; Keinan-Boker, Lital ; Cohen, Matan Joel ; Ben-Porat, Tair ; Gerasi, Heba ; Amun, Majd ; Abu-Gazala, Mahmud ; Khalaileh, Abed ; Mintz, Yoav ; Elazary, Ram</creator><creatorcontrib>Goldenshluger, Michael ; Goldenshluger, Ariela ; Keinan-Boker, Lital ; Cohen, Matan Joel ; Ben-Porat, Tair ; Gerasi, Heba ; Amun, Majd ; Abu-Gazala, Mahmud ; Khalaileh, Abed ; Mintz, Yoav ; Elazary, Ram</creatorcontrib><description>Objective
To evaluate the outcomes, weight loss predictors, and gastrointestinal symptoms of patients after laparoscopic sleeve gastrectomy (LSG).
Methods
The postoperative medical status of the patients was obtained retrospectively using a questionnaire and was compared to existing medical data before the surgery.
Results
We included 201 candidates, 178 patients completed mean of 3 years of follow-up. Mean excess body weight loss (%EWL) was 65.14% ± 15.74 at 6 months, 78.53% ± 20.28 at 12 months, and 74.32% ± 23.92 at 3 years after LSG. Older age (
P
= 0.018), higher baseline BMI (
P
= 0.003), and higher number of medications (
P
< 0.001) were negative predictors for EWL%. Total weekly hours of physical activity was found to be a positive predictor for EWL% (
P
= 0.008). Remission rates of co-morbidities were 83.5% for dyslipidemia (
P
< 0.001), 65.8% for hypertension (
P
< 0.001), 62.1% for type 2 diabetes mellitus (T2DM) (
P
< 0.001), and 60.7% for gastroesophageal reflux (GERD) (
P
< 0.001). Late gastrointestinal symptoms were as follows: emesis in 25.9%, constipation in 24.7%, diarrhea in 4.5%, food intolerance in 22.5% and alopecia in 42.7% of the patients.
Conclusion
Our study shows LSG as a potential tool in achieving almost 75% of EWL% with significant remission of co-morbidities, along with various late gastrointestinal symptoms.</description><identifier>ISSN: 1091-255X</identifier><identifier>EISSN: 1873-4626</identifier><identifier>DOI: 10.1007/s11605-017-3585-9</identifier><identifier>PMID: 28971291</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adult ; Age Factors ; Alopecia - etiology ; Body Mass Index ; Constipation - etiology ; Diabetes Mellitus, Type 2 - complications ; Diarrhea - etiology ; Drug Prescriptions ; Dyslipidemias - complications ; Exercise ; Female ; Follow-Up Studies ; Food Intolerance - etiology ; Gastrectomy - adverse effects ; Gastrectomy - methods ; Gastroenterology ; Gastroesophageal reflux ; Gastroesophageal Reflux - complications ; Gastrointestinal surgery ; Humans ; Hypertension - complications ; Laparoscopy ; Laparoscopy - adverse effects ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Obesity ; Obesity, Morbid - complications ; Obesity, Morbid - surgery ; Original Article ; Postoperative Period ; Preoperative Period ; Retrospective Studies ; Surgery ; Surveys and Questionnaires ; Treatment Outcome ; Vomiting - etiology ; Weight Loss</subject><ispartof>Journal of gastrointestinal surgery, 2017-12, Vol.21 (12), p.2009-2015</ispartof><rights>The Society for Surgery of the Alimentary Tract 2017</rights><rights>Journal of Gastrointestinal Surgery is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438t-5a8cf0a62323f42d091abf3d88a94923b0fa3ee711f8b22bc4087fd6b6c46cc03</citedby><cites>FETCH-LOGICAL-c438t-5a8cf0a62323f42d091abf3d88a94923b0fa3ee711f8b22bc4087fd6b6c46cc03</cites><orcidid>0000-0003-3701-2307</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11605-017-3585-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11605-017-3585-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28971291$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Goldenshluger, Michael</creatorcontrib><creatorcontrib>Goldenshluger, Ariela</creatorcontrib><creatorcontrib>Keinan-Boker, Lital</creatorcontrib><creatorcontrib>Cohen, Matan Joel</creatorcontrib><creatorcontrib>Ben-Porat, Tair</creatorcontrib><creatorcontrib>Gerasi, Heba</creatorcontrib><creatorcontrib>Amun, Majd</creatorcontrib><creatorcontrib>Abu-Gazala, Mahmud</creatorcontrib><creatorcontrib>Khalaileh, Abed</creatorcontrib><creatorcontrib>Mintz, Yoav</creatorcontrib><creatorcontrib>Elazary, Ram</creatorcontrib><title>Postoperative Outcomes, Weight Loss Predictors, and Late Gastrointestinal Symptoms Following Laparoscopic Sleeve Gastrectomy</title><title>Journal of gastrointestinal surgery</title><addtitle>J Gastrointest Surg</addtitle><addtitle>J Gastrointest Surg</addtitle><description>Objective
To evaluate the outcomes, weight loss predictors, and gastrointestinal symptoms of patients after laparoscopic sleeve gastrectomy (LSG).
Methods
The postoperative medical status of the patients was obtained retrospectively using a questionnaire and was compared to existing medical data before the surgery.
Results
We included 201 candidates, 178 patients completed mean of 3 years of follow-up. Mean excess body weight loss (%EWL) was 65.14% ± 15.74 at 6 months, 78.53% ± 20.28 at 12 months, and 74.32% ± 23.92 at 3 years after LSG. Older age (
P
= 0.018), higher baseline BMI (
P
= 0.003), and higher number of medications (
P
< 0.001) were negative predictors for EWL%. Total weekly hours of physical activity was found to be a positive predictor for EWL% (
P
= 0.008). Remission rates of co-morbidities were 83.5% for dyslipidemia (
P
< 0.001), 65.8% for hypertension (
P
< 0.001), 62.1% for type 2 diabetes mellitus (T2DM) (
P
< 0.001), and 60.7% for gastroesophageal reflux (GERD) (
P
< 0.001). Late gastrointestinal symptoms were as follows: emesis in 25.9%, constipation in 24.7%, diarrhea in 4.5%, food intolerance in 22.5% and alopecia in 42.7% of the patients.
Conclusion
Our study shows LSG as a potential tool in achieving almost 75% of EWL% with significant remission of co-morbidities, along with various late gastrointestinal symptoms.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Alopecia - etiology</subject><subject>Body Mass Index</subject><subject>Constipation - etiology</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diarrhea - etiology</subject><subject>Drug Prescriptions</subject><subject>Dyslipidemias - complications</subject><subject>Exercise</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Food Intolerance - etiology</subject><subject>Gastrectomy - adverse effects</subject><subject>Gastrectomy - methods</subject><subject>Gastroenterology</subject><subject>Gastroesophageal reflux</subject><subject>Gastroesophageal Reflux - complications</subject><subject>Gastrointestinal surgery</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Laparoscopy</subject><subject>Laparoscopy - adverse effects</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity, Morbid - complications</subject><subject>Obesity, Morbid - surgery</subject><subject>Original Article</subject><subject>Postoperative Period</subject><subject>Preoperative Period</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><subject>Surveys and Questionnaires</subject><subject>Treatment Outcome</subject><subject>Vomiting - etiology</subject><subject>Weight Loss</subject><issn>1091-255X</issn><issn>1873-4626</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU1rFTEYhYMo9kN_gBsJuHHRsfmaTLKUYqtwoYUquguZzDvXlJnJmGRaLvjjm-FeRYSuEpLnnOS8B6E3lHyghDTniVJJ6orQpuK1qiv9DB1T1fBKSCaflz3RtGJ1_eMInaR0RwpIqHqJjpjSDWWaHqPfNyHlMEO02d8Dvl6yCyOkM_wd_PZnxpuQEr6J0HmXQyzndurwxmbAVzblGPyUIWU_2QHf7sY5hzHhyzAM4cFP2wLONobkwuwdvh0A7g86KG7j7hV60dshwevDeoq-XX76evG52lxffbn4uKmc4CpXtVWuJ1YyzngvWFdS2bbnnVJWC814S3rLARpKe9Uy1jpBVNN3spVOSOcIP0Xv975zDL-W8l8z-uRgGOwEYUmGaiHFOpMVffcfeheWWOKtlJSKaKJEoeieciVditCbOfrRxp2hxKzVmH01pkzcrNUYXTRvD85LO0L3V_GniwKwPZDK1bSF-M_TT7o-Aj0rm4U</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Goldenshluger, Michael</creator><creator>Goldenshluger, Ariela</creator><creator>Keinan-Boker, Lital</creator><creator>Cohen, Matan Joel</creator><creator>Ben-Porat, Tair</creator><creator>Gerasi, Heba</creator><creator>Amun, Majd</creator><creator>Abu-Gazala, Mahmud</creator><creator>Khalaileh, Abed</creator><creator>Mintz, Yoav</creator><creator>Elazary, Ram</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3701-2307</orcidid></search><sort><creationdate>20171201</creationdate><title>Postoperative Outcomes, Weight Loss Predictors, and Late Gastrointestinal Symptoms Following Laparoscopic Sleeve Gastrectomy</title><author>Goldenshluger, Michael ; Goldenshluger, Ariela ; Keinan-Boker, Lital ; Cohen, Matan Joel ; Ben-Porat, Tair ; Gerasi, Heba ; Amun, Majd ; Abu-Gazala, Mahmud ; Khalaileh, Abed ; Mintz, Yoav ; Elazary, Ram</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-5a8cf0a62323f42d091abf3d88a94923b0fa3ee711f8b22bc4087fd6b6c46cc03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Alopecia - etiology</topic><topic>Body Mass Index</topic><topic>Constipation - etiology</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Diarrhea - etiology</topic><topic>Drug Prescriptions</topic><topic>Dyslipidemias - complications</topic><topic>Exercise</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Food Intolerance - etiology</topic><topic>Gastrectomy - adverse effects</topic><topic>Gastrectomy - methods</topic><topic>Gastroenterology</topic><topic>Gastroesophageal reflux</topic><topic>Gastroesophageal Reflux - complications</topic><topic>Gastrointestinal surgery</topic><topic>Humans</topic><topic>Hypertension - complications</topic><topic>Laparoscopy</topic><topic>Laparoscopy - adverse effects</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Obesity, Morbid - complications</topic><topic>Obesity, Morbid - surgery</topic><topic>Original Article</topic><topic>Postoperative Period</topic><topic>Preoperative Period</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><topic>Surveys and Questionnaires</topic><topic>Treatment Outcome</topic><topic>Vomiting - etiology</topic><topic>Weight Loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goldenshluger, Michael</creatorcontrib><creatorcontrib>Goldenshluger, Ariela</creatorcontrib><creatorcontrib>Keinan-Boker, Lital</creatorcontrib><creatorcontrib>Cohen, Matan Joel</creatorcontrib><creatorcontrib>Ben-Porat, Tair</creatorcontrib><creatorcontrib>Gerasi, Heba</creatorcontrib><creatorcontrib>Amun, Majd</creatorcontrib><creatorcontrib>Abu-Gazala, Mahmud</creatorcontrib><creatorcontrib>Khalaileh, Abed</creatorcontrib><creatorcontrib>Mintz, Yoav</creatorcontrib><creatorcontrib>Elazary, Ram</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of gastrointestinal surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goldenshluger, Michael</au><au>Goldenshluger, Ariela</au><au>Keinan-Boker, Lital</au><au>Cohen, Matan Joel</au><au>Ben-Porat, Tair</au><au>Gerasi, Heba</au><au>Amun, Majd</au><au>Abu-Gazala, Mahmud</au><au>Khalaileh, Abed</au><au>Mintz, Yoav</au><au>Elazary, Ram</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Postoperative Outcomes, Weight Loss Predictors, and Late Gastrointestinal Symptoms Following Laparoscopic Sleeve Gastrectomy</atitle><jtitle>Journal of gastrointestinal surgery</jtitle><stitle>J Gastrointest Surg</stitle><addtitle>J Gastrointest Surg</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>21</volume><issue>12</issue><spage>2009</spage><epage>2015</epage><pages>2009-2015</pages><issn>1091-255X</issn><eissn>1873-4626</eissn><abstract>Objective
To evaluate the outcomes, weight loss predictors, and gastrointestinal symptoms of patients after laparoscopic sleeve gastrectomy (LSG).
Methods
The postoperative medical status of the patients was obtained retrospectively using a questionnaire and was compared to existing medical data before the surgery.
Results
We included 201 candidates, 178 patients completed mean of 3 years of follow-up. Mean excess body weight loss (%EWL) was 65.14% ± 15.74 at 6 months, 78.53% ± 20.28 at 12 months, and 74.32% ± 23.92 at 3 years after LSG. Older age (
P
= 0.018), higher baseline BMI (
P
= 0.003), and higher number of medications (
P
< 0.001) were negative predictors for EWL%. Total weekly hours of physical activity was found to be a positive predictor for EWL% (
P
= 0.008). Remission rates of co-morbidities were 83.5% for dyslipidemia (
P
< 0.001), 65.8% for hypertension (
P
< 0.001), 62.1% for type 2 diabetes mellitus (T2DM) (
P
< 0.001), and 60.7% for gastroesophageal reflux (GERD) (
P
< 0.001). Late gastrointestinal symptoms were as follows: emesis in 25.9%, constipation in 24.7%, diarrhea in 4.5%, food intolerance in 22.5% and alopecia in 42.7% of the patients.
Conclusion
Our study shows LSG as a potential tool in achieving almost 75% of EWL% with significant remission of co-morbidities, along with various late gastrointestinal symptoms.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>28971291</pmid><doi>10.1007/s11605-017-3585-9</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-3701-2307</orcidid></addata></record> |
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| ispartof | Journal of gastrointestinal surgery, 2017-12, Vol.21 (12), p.2009-2015 |
| issn | 1091-255X 1873-4626 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1946428970 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Age Factors Alopecia - etiology Body Mass Index Constipation - etiology Diabetes Mellitus, Type 2 - complications Diarrhea - etiology Drug Prescriptions Dyslipidemias - complications Exercise Female Follow-Up Studies Food Intolerance - etiology Gastrectomy - adverse effects Gastrectomy - methods Gastroenterology Gastroesophageal reflux Gastroesophageal Reflux - complications Gastrointestinal surgery Humans Hypertension - complications Laparoscopy Laparoscopy - adverse effects Male Medicine Medicine & Public Health Middle Aged Obesity Obesity, Morbid - complications Obesity, Morbid - surgery Original Article Postoperative Period Preoperative Period Retrospective Studies Surgery Surveys and Questionnaires Treatment Outcome Vomiting - etiology Weight Loss |
| title | Postoperative Outcomes, Weight Loss Predictors, and Late Gastrointestinal Symptoms Following Laparoscopic Sleeve Gastrectomy |
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