Elucidation of the E-Amide Preference of N‑Acyl Azoles

The conformational properties of N-acyl azoles (imidazole, pyrazole, and triazole) were examined. The N-2′,4′,6′-trichlorobenzoyl azoles were stable in methanol at room temperature, and no hydrolyzed products were observed over 7 days in the presence of 5% trifluoroacetic acid or 5% triethylamine in...

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Veröffentlicht in:Journal of organic chemistry 2017-11, Vol.82 (21), p.11370-11382
Hauptverfasser: Takahashi, Yuka, Ikeda, Hirotaka, Kanase, Yuki, Makino, Kosho, Tabata, Hidetsugu, Oshitari, Tetsuta, Inagaki, Satoshi, Otani, Yuko, Natsugari, Hideaki, Takahashi, Hideyo, Ohwada, Tomohiko
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Sprache:eng
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