Thoracoscopic Decortication of Stage III Tuberculous Empyema Is Effective and Safe in Selected Cases
Open decortication of advanced tuberculous empyema remains standard of care. As with other aspects of thoracic surgery, minimally invasive approaches are making inroads into procedures traditionally performed open. In this retrospective analysis, we sought to examine feasibility, efficacy, and outco...
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Veröffentlicht in: | The Annals of thoracic surgery 2017-11, Vol.104 (5), p.1688-1694 |
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container_title | The Annals of thoracic surgery |
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creator | Kumar, Arvind Asaf, Belal B. Lingaraju, Vijay C. Yendamuri, Sai Pulle, Mohan V. Sood, Jayashree |
description | Open decortication of advanced tuberculous empyema remains standard of care. As with other aspects of thoracic surgery, minimally invasive approaches are making inroads into procedures traditionally performed open. In this retrospective analysis, we sought to examine feasibility, efficacy, and outcomes of thoracoscopic decortication of stage III tuberculous empyema in our experience.
The records of all patients in whom thoracoscopic decortication of stage III tuberculous empyema was performed between March 2012 and December 2015 were examined. Demographic and perioperative data were analyzed to assess the surgical outcomes of this study group. To assess long-term efficacy, patients were followed for a minimum of 6 months.
One hundred patients fit the study criteria, of these 67 were men. Ninety cases were successfully completed thoracoscopically. Mean operative time was 204 ± 34.2 minutes with mean blood loss of 384 ± 28 mL. Median chest drain duration and hospital stay was 7 days. There was no perioperative deaths. Morbidity rate was 33%, composed mostly of prolonged air leak (29%). Six-month follow-up revealed completely expanded lung in all patients except one with small apical asymptomatic air space. Intraoperative cultures were positive for mycobacteria in 25% patients. Six (6%) of these patients had multidrug-resistant tuberculosis and required a modification in their antituberculous therapy.
Thoracoscopic decortication of advanced tuberculous empyema is feasible, safe, and effective with good short- and long-term results in selected patients. In a substantial portion of patients, operative cultures required modifying drug treatment to treat underlying tuberculosis. |
doi_str_mv | 10.1016/j.athoracsur.2017.06.038 |
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The records of all patients in whom thoracoscopic decortication of stage III tuberculous empyema was performed between March 2012 and December 2015 were examined. Demographic and perioperative data were analyzed to assess the surgical outcomes of this study group. To assess long-term efficacy, patients were followed for a minimum of 6 months.
One hundred patients fit the study criteria, of these 67 were men. Ninety cases were successfully completed thoracoscopically. Mean operative time was 204 ± 34.2 minutes with mean blood loss of 384 ± 28 mL. Median chest drain duration and hospital stay was 7 days. There was no perioperative deaths. Morbidity rate was 33%, composed mostly of prolonged air leak (29%). Six-month follow-up revealed completely expanded lung in all patients except one with small apical asymptomatic air space. Intraoperative cultures were positive for mycobacteria in 25% patients. Six (6%) of these patients had multidrug-resistant tuberculosis and required a modification in their antituberculous therapy.
Thoracoscopic decortication of advanced tuberculous empyema is feasible, safe, and effective with good short- and long-term results in selected patients. In a substantial portion of patients, operative cultures required modifying drug treatment to treat underlying tuberculosis.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2017.06.038</identifier><identifier>PMID: 28964422</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adult ; Age Factors ; Chest Tubes ; Cohort Studies ; Empyema, Tuberculous - diagnostic imaging ; Empyema, Tuberculous - surgery ; Female ; Humans ; Length of Stay ; Male ; Middle Aged ; Mycobacterium tuberculosis - isolation & purification ; Patient Safety ; Postoperative Care - methods ; Prognosis ; Respiratory Function Tests ; Retrospective Studies ; Risk Assessment ; Sex Factors ; Thoracic Surgery, Video-Assisted - methods ; Thoracoscopy - methods ; Tomography, X-Ray Computed - methods ; Treatment Outcome ; Young Adult</subject><ispartof>The Annals of thoracic surgery, 2017-11, Vol.104 (5), p.1688-1694</ispartof><rights>2017 The Society of Thoracic Surgeons</rights><rights>Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c490t-fc977fbaa5303793295f3dfab4d20c6f4aea35e0f6872b6d526b92f4ebf783d3</citedby><cites>FETCH-LOGICAL-c490t-fc977fbaa5303793295f3dfab4d20c6f4aea35e0f6872b6d526b92f4ebf783d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28964422$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kumar, Arvind</creatorcontrib><creatorcontrib>Asaf, Belal B.</creatorcontrib><creatorcontrib>Lingaraju, Vijay C.</creatorcontrib><creatorcontrib>Yendamuri, Sai</creatorcontrib><creatorcontrib>Pulle, Mohan V.</creatorcontrib><creatorcontrib>Sood, Jayashree</creatorcontrib><title>Thoracoscopic Decortication of Stage III Tuberculous Empyema Is Effective and Safe in Selected Cases</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Open decortication of advanced tuberculous empyema remains standard of care. As with other aspects of thoracic surgery, minimally invasive approaches are making inroads into procedures traditionally performed open. In this retrospective analysis, we sought to examine feasibility, efficacy, and outcomes of thoracoscopic decortication of stage III tuberculous empyema in our experience.
The records of all patients in whom thoracoscopic decortication of stage III tuberculous empyema was performed between March 2012 and December 2015 were examined. Demographic and perioperative data were analyzed to assess the surgical outcomes of this study group. To assess long-term efficacy, patients were followed for a minimum of 6 months.
One hundred patients fit the study criteria, of these 67 were men. Ninety cases were successfully completed thoracoscopically. Mean operative time was 204 ± 34.2 minutes with mean blood loss of 384 ± 28 mL. Median chest drain duration and hospital stay was 7 days. There was no perioperative deaths. Morbidity rate was 33%, composed mostly of prolonged air leak (29%). Six-month follow-up revealed completely expanded lung in all patients except one with small apical asymptomatic air space. Intraoperative cultures were positive for mycobacteria in 25% patients. Six (6%) of these patients had multidrug-resistant tuberculosis and required a modification in their antituberculous therapy.
Thoracoscopic decortication of advanced tuberculous empyema is feasible, safe, and effective with good short- and long-term results in selected patients. In a substantial portion of patients, operative cultures required modifying drug treatment to treat underlying tuberculosis.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Chest Tubes</subject><subject>Cohort Studies</subject><subject>Empyema, Tuberculous - diagnostic imaging</subject><subject>Empyema, Tuberculous - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mycobacterium tuberculosis - isolation & purification</subject><subject>Patient Safety</subject><subject>Postoperative Care - methods</subject><subject>Prognosis</subject><subject>Respiratory Function Tests</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Sex Factors</subject><subject>Thoracic Surgery, Video-Assisted - methods</subject><subject>Thoracoscopy - methods</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtu3CAUhlGVqpmkfYWIZTZ2MRgwy2aStpYidTGzRxgODSPbTMGOlLcPyaTNsqtz-8_tQwg3pG5II74earM8xGRsXlNNSSNrImrCug9o03BOK0G5OkMbQgirWiX5ObrI-VBCWsqf0DntlGhbSjfI7V_nxGzjMVh8CzamJVizhDjj6PFuMb8B932P9-sAya5jXDO-m45PMBncF9d7sEt4BGxmh3fGAw4z3sFYsuDw1mTIn9FHb8YMX97sJdp_v9tvf1b3v37022_3lW0VWSpvlZR-MIYzwqRiVHHPnDdD6yixwrcGDONAvOgkHYTjVAyK-hYGLzvm2CW6Po09pvhnhbzoKWQL42hmKFfrRrVcNlISUaTdSWpTzDmB18cUJpOedEP0C2J90O-I9QtiTYQuiEvr1duWdZjA_Wv8y7QIbk4CKK8-Bkg62wCzBRdSgaJdDP_f8gyk_JNL</recordid><startdate>201711</startdate><enddate>201711</enddate><creator>Kumar, Arvind</creator><creator>Asaf, Belal B.</creator><creator>Lingaraju, Vijay C.</creator><creator>Yendamuri, Sai</creator><creator>Pulle, Mohan V.</creator><creator>Sood, Jayashree</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201711</creationdate><title>Thoracoscopic Decortication of Stage III Tuberculous Empyema Is Effective and Safe in Selected Cases</title><author>Kumar, Arvind ; Asaf, Belal B. ; Lingaraju, Vijay C. ; Yendamuri, Sai ; Pulle, Mohan V. ; Sood, Jayashree</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c490t-fc977fbaa5303793295f3dfab4d20c6f4aea35e0f6872b6d526b92f4ebf783d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Chest Tubes</topic><topic>Cohort Studies</topic><topic>Empyema, Tuberculous - diagnostic imaging</topic><topic>Empyema, Tuberculous - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mycobacterium tuberculosis - isolation & purification</topic><topic>Patient Safety</topic><topic>Postoperative Care - methods</topic><topic>Prognosis</topic><topic>Respiratory Function Tests</topic><topic>Retrospective Studies</topic><topic>Risk Assessment</topic><topic>Sex Factors</topic><topic>Thoracic Surgery, Video-Assisted - methods</topic><topic>Thoracoscopy - methods</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kumar, Arvind</creatorcontrib><creatorcontrib>Asaf, Belal B.</creatorcontrib><creatorcontrib>Lingaraju, Vijay C.</creatorcontrib><creatorcontrib>Yendamuri, Sai</creatorcontrib><creatorcontrib>Pulle, Mohan V.</creatorcontrib><creatorcontrib>Sood, Jayashree</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumar, Arvind</au><au>Asaf, Belal B.</au><au>Lingaraju, Vijay C.</au><au>Yendamuri, Sai</au><au>Pulle, Mohan V.</au><au>Sood, Jayashree</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thoracoscopic Decortication of Stage III Tuberculous Empyema Is Effective and Safe in Selected Cases</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2017-11</date><risdate>2017</risdate><volume>104</volume><issue>5</issue><spage>1688</spage><epage>1694</epage><pages>1688-1694</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Open decortication of advanced tuberculous empyema remains standard of care. As with other aspects of thoracic surgery, minimally invasive approaches are making inroads into procedures traditionally performed open. In this retrospective analysis, we sought to examine feasibility, efficacy, and outcomes of thoracoscopic decortication of stage III tuberculous empyema in our experience.
The records of all patients in whom thoracoscopic decortication of stage III tuberculous empyema was performed between March 2012 and December 2015 were examined. Demographic and perioperative data were analyzed to assess the surgical outcomes of this study group. To assess long-term efficacy, patients were followed for a minimum of 6 months.
One hundred patients fit the study criteria, of these 67 were men. Ninety cases were successfully completed thoracoscopically. Mean operative time was 204 ± 34.2 minutes with mean blood loss of 384 ± 28 mL. Median chest drain duration and hospital stay was 7 days. There was no perioperative deaths. Morbidity rate was 33%, composed mostly of prolonged air leak (29%). Six-month follow-up revealed completely expanded lung in all patients except one with small apical asymptomatic air space. Intraoperative cultures were positive for mycobacteria in 25% patients. Six (6%) of these patients had multidrug-resistant tuberculosis and required a modification in their antituberculous therapy.
Thoracoscopic decortication of advanced tuberculous empyema is feasible, safe, and effective with good short- and long-term results in selected patients. In a substantial portion of patients, operative cultures required modifying drug treatment to treat underlying tuberculosis.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>28964422</pmid><doi>10.1016/j.athoracsur.2017.06.038</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Age Factors Chest Tubes Cohort Studies Empyema, Tuberculous - diagnostic imaging Empyema, Tuberculous - surgery Female Humans Length of Stay Male Middle Aged Mycobacterium tuberculosis - isolation & purification Patient Safety Postoperative Care - methods Prognosis Respiratory Function Tests Retrospective Studies Risk Assessment Sex Factors Thoracic Surgery, Video-Assisted - methods Thoracoscopy - methods Tomography, X-Ray Computed - methods Treatment Outcome Young Adult |
title | Thoracoscopic Decortication of Stage III Tuberculous Empyema Is Effective and Safe in Selected Cases |
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