Aspergillus myofasciitis in a chronic granulomatous disease patient: first case report
Aspergillus myofasciitis is a rare infection of the muscles and their fascial sheaths that has been reported in patients with immune deficiencies of various kinds but, until now, not with chronic granulomatous disease (CGD). Patients affected by CGD are at high risk of invasive aspergillus infection...
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| Veröffentlicht in: | Le infezioni in medicina 2017-09, Vol.25 (3), p.270-273 |
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| creator | Camanni, Guido Sgrelli, Alessio Ferraro, Luigi |
| description | Aspergillus myofasciitis is a rare infection of the muscles and their fascial sheaths that has been reported in patients with immune deficiencies of various kinds but, until now, not with chronic granulomatous disease (CGD). Patients affected by CGD are at high risk of invasive aspergillus infections. The case described involves a 14-year-old boy with a severe autosomal recessive CGD who was admitted to hospital with an Aspergillus myofasciitis of the left forearm. He was treated with liposomal amphotericin for 14 days and then with oral voriconazole for three months with an excellent clinical outcome. He did not evidence any recurrence in the following 30 months using itraconazole prophylaxis. |
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Patients affected by CGD are at high risk of invasive aspergillus infections. The case described involves a 14-year-old boy with a severe autosomal recessive CGD who was admitted to hospital with an Aspergillus myofasciitis of the left forearm. He was treated with liposomal amphotericin for 14 days and then with oral voriconazole for three months with an excellent clinical outcome. 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Patients affected by CGD are at high risk of invasive aspergillus infections. The case described involves a 14-year-old boy with a severe autosomal recessive CGD who was admitted to hospital with an Aspergillus myofasciitis of the left forearm. He was treated with liposomal amphotericin for 14 days and then with oral voriconazole for three months with an excellent clinical outcome. 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| ispartof | Le infezioni in medicina, 2017-09, Vol.25 (3), p.270-273 |
| issn | 1124-9390 |
| language | eng |
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| source | MEDLINE; Free E-Journal (出版社公開部分のみ） |
| subjects | Adolescent Amphotericin B - therapeutic use Antifungal Agents - therapeutic use Aspergillosis - drug therapy Aspergillosis - etiology Aspergillosis - microbiology Aspergillosis - surgery Aspergillus fumigatus - isolation & purification Combined Modality Therapy Debridement Drug Therapy, Combination Fasciitis - drug therapy Fasciitis - etiology Fasciitis - microbiology Fasciitis - surgery Forearm Granulomatous Disease, Chronic - complications Humans Interferon-gamma - therapeutic use Itraconazole - therapeutic use Male Pyomyositis - drug therapy Pyomyositis - etiology Pyomyositis - microbiology Pyomyositis - surgery Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use |
| title | Aspergillus myofasciitis in a chronic granulomatous disease patient: first case report |
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