Short fluorodeoxyuridine exposure of different human glioblastoma lines induces high-level accumulation of S-phase cells that avidly incorporate super(125)I-iododeoxyuridine

Purpose Radio-iododeoxyuridine (IdUrd) is a potential Auger radiation therapy agent incorporated into DNA during the synthesis phase. In this study we sought to optimise S-phase targeting by modulating cellular cycling and radio-ldUrd DNA incorporation using short non-toxic fluorodeoxyuridine (FdUrd...

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Veröffentlicht in:European journal of nuclear medicine and molecular imaging 2006-05, Vol.33 (5), p.613-620
Hauptverfasser: Perillo-Adamer, F, Delaloye, AB, Genton, C S, Schaffland, A O, Dupertuis, Y M, Buchegger, F
Format: Artikel
Sprache:eng
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