Polyion complex micelles for photodynamic therapy: Incorporation of dendritic photosensitizer excitable at long wavelength relevant to improved tissue-penetrating property

A polymeric micelle (DPcZn/m) system, which is formed via an electrostatic interaction of anionic dendrimer phthalocyanine (DPcZn) and poly(ethylene glycol)-poly( l-lysine) block copolymers (PEG- b-PLL), was prepared for use as an effective photosensitizer for photodynamic therapy. DPcZn/m exhibited...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of controlled release 2006-06, Vol.113 (1), p.73-79
Hauptverfasser:	Jang, Woo-Dong, Nakagishi, Yoshinori, Nishiyama, Nobuhiro, Kawauchi, Satoko, Morimoto, Yuji, Kikuchi, Makoto, Kataoka, Kazunori
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Culture Techniques Cell Survival - radiation effects Dendrimer Dendrimers - chemical synthesis Dendrimers - chemistry Dendrimers - metabolism Dendrimers - radiation effects Dendrimers - toxicity Dose-Response Relationship, Drug General pharmacology HeLa Cells Humans Hydrogen-Ion Concentration Indoles - chemical synthesis Indoles - chemistry Indoles - metabolism Indoles - radiation effects Indoles - toxicity Light Medical sciences Micelles Oxygen Consumption Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Photochemotherapy Photodynamic therapy Photosensitizer Phthalocyanine Polyamines Polyethylene Glycols - chemistry Polyethylene Glycols - toxicity Polylysine - chemistry Polylysine - toxicity Polymeric micelle Polymers Reactive Oxygen Species - metabolism Solubility Static Electricity Water - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!