Protective effect of xanthohumol against age-related brain damage

It has been recently shown that xanthohumol, a flavonoid present in hops, possesses antioxidant, anti-inflammatory and chemopreventive properties. However, its role in the aging brain has not been addressed so far. Therefore, this study aimed to investigate the possible neuroprotective activity of x...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2017-11, Vol.49, p.133-140
Hauptverfasser:	Rancán, Lisa, Paredes, Sergio D., García, Irene, Muñoz, Pedro, García, Cruz, López de Hontanar, Guzmán, de la Fuente, Mónica, Vara, Elena, Tresguerres, Jesús A.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Apoptosis Apoptosis Regulatory Proteins - genetics Apoptosis Regulatory Proteins - metabolism Biomarkers - metabolism Brain Brain - immunology Brain - metabolism Cognitive Dysfunction - immunology Cognitive Dysfunction - metabolism Cognitive Dysfunction - prevention & control Dietary Supplements Encephalitis - immunology Encephalitis - metabolism Encephalitis - prevention & control Flavonoids - administration & dosage Flavonoids - therapeutic use Gene Expression Regulation, Developmental Glial Fibrillary Acidic Protein - genetics Glial Fibrillary Acidic Protein - metabolism Inflammation Inflammation Mediators - metabolism Male Mice, Inbred Strains Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neurons - immunology Neurons - metabolism Neuroprotective Agents - administration & dosage Neuroprotective Agents - therapeutic use Propiophenones - administration & dosage Propiophenones - therapeutic use Synaptophysin - genetics Synaptophysin - metabolism Xanthohumol
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