Nucleophilic Substitution of P‑Stereogenic Chlorophosphines: Mechanism, Stereochemistry, and Stereoselective Conversions of Diastereomeric Secondary Phosphine Oxides to Tertiary Phosphines

A diastereomeric mixture of secondary phosphine oxide is stereospecifically converted to chlorophosphine salt by treatment with oxalyl chloride, which stereoselectively affords P-inverted or retained tertiary phosphines, depending on the substitution with aliphatic or aromatic Grignard reagents, res...

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Veröffentlicht in:	Organic letters 2017-10, Vol.19 (19), p.5384-5387
Hauptverfasser:	Ye, Jing-Jing, Nie, Shao-Zhen, Wang, Ji-Ping, Wen, Jing-Hong, Zhang, Yu, Qiu, Mao-Ran, Zhao, Chang-Qiu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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