Enlarging the gas access channel to the active site renders the regulatory hydrogenase HupUV of Rhodobacter capsulatus O sub(2) sensitive without affecting its transductory activity

In the photosynthetic bacterium Rhodobacter capsulatus, the synthesis of the energy-producing hydrogenase, HupSL, is regulated by the substrate H sub(2), which is detected by a regulatory hydrogenase, HupUV. The HupUV protein exhibits typical features of [NiFe] hydrogenases but, interestingly, is re...

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Veröffentlicht in:The FEBS journal 2005-08, Vol.272 (15), p.3899-3908
Hauptverfasser: Duche, Ophelie, Elsen, Sylvie, Cournac, Laurent, Colbeau, Annette
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Sprache:eng
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