Effect of total alkaloid extract of local Sophora alopecuroides on minimum inhibitory concentration and intracellular accumulation of ciprofloxacin, and acrA expression in highly resistant Escherichia coli clones

•Herbal plants, including Sophora spp., distributed worldwide are rich in secondary metabolites such as alkaloids.•Sophora alopecuroides alkaloid extract and matrine reduced the ciprofloxacin MIC in highly resistant E. coli clones.•The alkaloid extract and matrine enhanced intracellular accumulation...

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Veröffentlicht in:Journal of global antimicrobial resistance. 2018-03, Vol.12, p.55-60
Hauptverfasser: Pourahmad Jaktaji, Razieh, Mohammadi, Parvin
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Sprache:eng
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