Recombinant allergen and peptide-based approaches for allergy prevention by oral tolerance

Several studies conducted in animal models for immunologically-mediated hypersensitivity diseases have shown that oral administration of antigens early in life can prevent the development of specific humoral and cellular immune responses and thus hypersensitivity reactions to the respective antigens...

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Veröffentlicht in:	Seminars in immunology 2017-04, Vol.30, p.67-80
Hauptverfasser:	Campana, Raffaela, Huang, Huey-Jy, Freidl, Raphaela, Linhart, Birgit, Vrtala, Susanne, Wekerle, Thomas, Karaulov, Alexander, Valenta, Rudolf
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Allergen Allergen-specific immunotherapy Allergens - genetics Allergens - immunology Allergens - therapeutic use Allergy Allergy prevention Animals Humans Hypersensitivity - immunology Hypersensitivity - therapy Immune Tolerance Immunodominant Epitopes - genetics Immunoglobulin E - metabolism Oral tolerance induction Peptides - genetics Peptides - therapeutic use Recombinant allergen Recombinant Proteins - genetics Recombinant Proteins - therapeutic use T cell peptides
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