Role of Glutathione-S-Transferase Family Genes in Male Infertility

Polymorphisms of xenobiotic detoxification genes GSTT1 and GSTM1 and activity of glutathione system enzymes were studied in men with infertility. The frequency of deletion variant of GSTT1 gene in men with infertility was by 2 times higher than in fertile men. Deletion variant of GSTM1 gene was 1.4-...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2017-09, Vol.163 (5), p.643-645
Hauptverfasser:	Kolesnikova, L. I., Kurashova, N. A., Bairova, T. A., Dolgikh, M. I., Ershova, O. A., Dashiev, B. G., Korytov, L. I., Koroleva, N. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomedical and Life Sciences Biomedicine Cell Biology Genes Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease - genetics Glutathione - metabolism Glutathione Disulfide - metabolism Glutathione transferase Glutathione Transferase - genetics Glutathione Transferase - physiology Humans Infertility Infertility, Male - enzymology Infertility, Male - genetics Infertility, Male - physiopathology Internal Medicine Laboratory Medicine Male Pathology Polymorphism, Genetic - genetics Thiols Xenobiotics
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