Caspase-11 deficiency impairs neutrophil recruitment and bacterial clearance in the early stage of pulmonary Klebsiella pneumoniae infection

Klebsiella pneumoniae (K. pneumoniae) is a gram-negative pathogen, and Klebsiella pneumonia is one of the most common nosocomial infections. Canonical NLRP3 and NLRC4 inflammasome was found involved in innate immune response against K. pneumoniae, but the role of caspase-11 in K. pneumoniae infectio...

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