Immunomodulation of mesenchymal stem cells in discogenic pain

Back pain is a highly prevalent health problem in the world today and has a great economic impact on health-care budgets. Intervertebral disc (IVD) degeneration has been identified as a main cause of back pain. Inflammatory cytokines produced by macrophages or disc cells in an inflammatory environme...

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Veröffentlicht in:	The spine journal 2018-02, Vol.18 (2), p.330-342
Hauptverfasser:	Miguélez-Rivera, Laura, Pérez-Castrillo, Saúl, González-Fernández, Maria Luisa, Prieto-Fernández, Julio Gabriel, López-González, María Elisa, García-Cosamalón, José, Villar-Suárez, Vega
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Back Pain - metabolism Back Pain - pathology Conditioned medium Culture Media, Conditioned - pharmacology Cytokines Cytokines - metabolism Discogenic pain Humans Immunomodulation Inflammation - metabolism Inflammation - pathology Intervertebral Disc - metabolism Intervertebral Disc - pathology Intervertebral Disc Degeneration - metabolism Intervertebral Disc Degeneration - pathology Mesenchymal stem cells Mesenchymal Stem Cells - cytology Rat model Rats
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