Comparison of 7 Surgical Interventions for Lumbar Disc Herniation: A Network Meta-analysis

The number of interventions on intervertebral discs rapidly increased and the treatment options for lumbar disc surgery quickly evolved. It is important that the safety and efficacy of all new innovative procedures be compared with currently accepted forms of treatment; however, the previous pairwis...

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Veröffentlicht in:Pain physician 2017-09, Vol.20 (6), p.E863-E871
Hauptverfasser: Feng, Fan, Xu, Qianqian, Yan, Feifei, Xie, Yuanlong, Deng, Zhouming, Hu, Chao, Zhu, Xiaobin, Cai, Lin
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container_end_page E871
container_issue 6
container_start_page E863
container_title Pain physician
container_volume 20
creator Feng, Fan
Xu, Qianqian
Yan, Feifei
Xie, Yuanlong
Deng, Zhouming
Hu, Chao
Zhu, Xiaobin
Cai, Lin
description The number of interventions on intervertebral discs rapidly increased and the treatment options for lumbar disc surgery quickly evolved. It is important that the safety and efficacy of all new innovative procedures be compared with currently accepted forms of treatment; however, the previous pairwise meta-analyses could not develop the hierarchy of these treatments. The purpose of the study is to perform a network meta-analysis to evaluate the clinical results of 7 surgical interventions for the treatment of lumbar disc herniation. Network meta-analysis of randomized controlled trials (RCTs) for multiple treatment comparisons of lumbar disc herniation. We performed a Bayesian-framework network meta-analysis of RCTs to compare 7 surgical interventions for people with lumbar disc herniation. The eligible RCTs were identified by searching Embase, Pubmed, the Cochrane Central Register of Controlled Trials (CENTRAL), and Google scholar. Data from 3 outcomes (success, complications, and reoperation rate) were independently extracted by 2 authors. A total of 29 RCTs including 3,146 participants were finally included into this article. Our meta-analysis provides hierarchies of these 7 interventions. For the success rate the rank probability (from best to worst): percutaneous endoscopic lumber discectomy (PELD) > standard open discectomy (SOD) > standard open microsurgical discectomy (SOMD) > chemonucleolysis (CN) > microendoscopic discectomy (MED) > percutaneous laser disc decompression (PLDD) > automated percutaneous lumber discectomy (APLD). For the complication rate the rank probability (from best to worst): PELD > SOMD > SOD > MED > PLDD > CN > APLD. For the reoperation rate the rank probability (from best to worst): SOMD > SOD > MED > PLDD > PELD > CN > APLD. The limitations of this network meta-analysis include the range of study populations and inconformity of the follow-up times and outcome measurements. This meta-analysis provides evidence that PELD might be the best choice to increase the success rate and decrease the complication rate, moreover SOMD might be the best option to drop the reoperation rate. APLD might lead to the lowest success rate and the highest complication and reoperation rate. Higher quality RCTs and direct head to head trials are needed to confirm these results.Key words: Lumbar disc herniation, discectomy, minimally invasive surgery, network meta-analysis.
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It is important that the safety and efficacy of all new innovative procedures be compared with currently accepted forms of treatment; however, the previous pairwise meta-analyses could not develop the hierarchy of these treatments. The purpose of the study is to perform a network meta-analysis to evaluate the clinical results of 7 surgical interventions for the treatment of lumbar disc herniation. Network meta-analysis of randomized controlled trials (RCTs) for multiple treatment comparisons of lumbar disc herniation. We performed a Bayesian-framework network meta-analysis of RCTs to compare 7 surgical interventions for people with lumbar disc herniation. The eligible RCTs were identified by searching Embase, Pubmed, the Cochrane Central Register of Controlled Trials (CENTRAL), and Google scholar. Data from 3 outcomes (success, complications, and reoperation rate) were independently extracted by 2 authors. A total of 29 RCTs including 3,146 participants were finally included into this article. Our meta-analysis provides hierarchies of these 7 interventions. For the success rate the rank probability (from best to worst): percutaneous endoscopic lumber discectomy (PELD) &gt; standard open discectomy (SOD) &gt; standard open microsurgical discectomy (SOMD) &gt; chemonucleolysis (CN) &gt; microendoscopic discectomy (MED) &gt; percutaneous laser disc decompression (PLDD) &gt; automated percutaneous lumber discectomy (APLD). For the complication rate the rank probability (from best to worst): PELD &gt; SOMD &gt; SOD &gt; MED &gt; PLDD &gt; CN &gt; APLD. For the reoperation rate the rank probability (from best to worst): SOMD &gt; SOD &gt; MED &gt; PLDD &gt; PELD &gt; CN &gt; APLD. The limitations of this network meta-analysis include the range of study populations and inconformity of the follow-up times and outcome measurements. This meta-analysis provides evidence that PELD might be the best choice to increase the success rate and decrease the complication rate, moreover SOMD might be the best option to drop the reoperation rate. APLD might lead to the lowest success rate and the highest complication and reoperation rate. Higher quality RCTs and direct head to head trials are needed to confirm these results.Key words: Lumbar disc herniation, discectomy, minimally invasive surgery, network meta-analysis.</description><identifier>ISSN: 1533-3159</identifier><identifier>EISSN: 2150-1149</identifier><identifier>PMID: 28934804</identifier><language>eng</language><publisher>United States: American Society of Interventional Pain Physician</publisher><subject>Decompression, Surgical - methods ; Decompression, Surgical - standards ; Diskectomy - methods ; Diskectomy - standards ; Diskectomy, Percutaneous - methods ; Diskectomy, Percutaneous - standards ; Endoscopy - methods ; Endoscopy - standards ; Humans ; Intervertebral Disc - diagnostic imaging ; Intervertebral Disc - surgery ; Intervertebral Disc Degeneration - diagnostic imaging ; Intervertebral Disc Degeneration - surgery ; Intervertebral Disc Displacement - diagnostic imaging ; Intervertebral Disc Displacement - surgery ; Laser discs ; Lumbar Vertebrae - diagnostic imaging ; Lumbar Vertebrae - surgery ; Meta-analysis ; Minimally Invasive Surgical Procedures - methods ; Minimally Invasive Surgical Procedures - standards ; Network Meta-Analysis ; Randomized Controlled Trials as Topic - methods ; Reoperation - methods ; Reoperation - standards ; Success</subject><ispartof>Pain physician, 2017-09, Vol.20 (6), p.E863-E871</ispartof><rights>2017. 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It is important that the safety and efficacy of all new innovative procedures be compared with currently accepted forms of treatment; however, the previous pairwise meta-analyses could not develop the hierarchy of these treatments. The purpose of the study is to perform a network meta-analysis to evaluate the clinical results of 7 surgical interventions for the treatment of lumbar disc herniation. Network meta-analysis of randomized controlled trials (RCTs) for multiple treatment comparisons of lumbar disc herniation. We performed a Bayesian-framework network meta-analysis of RCTs to compare 7 surgical interventions for people with lumbar disc herniation. The eligible RCTs were identified by searching Embase, Pubmed, the Cochrane Central Register of Controlled Trials (CENTRAL), and Google scholar. Data from 3 outcomes (success, complications, and reoperation rate) were independently extracted by 2 authors. A total of 29 RCTs including 3,146 participants were finally included into this article. Our meta-analysis provides hierarchies of these 7 interventions. For the success rate the rank probability (from best to worst): percutaneous endoscopic lumber discectomy (PELD) &gt; standard open discectomy (SOD) &gt; standard open microsurgical discectomy (SOMD) &gt; chemonucleolysis (CN) &gt; microendoscopic discectomy (MED) &gt; percutaneous laser disc decompression (PLDD) &gt; automated percutaneous lumber discectomy (APLD). For the complication rate the rank probability (from best to worst): PELD &gt; SOMD &gt; SOD &gt; MED &gt; PLDD &gt; CN &gt; APLD. For the reoperation rate the rank probability (from best to worst): SOMD &gt; SOD &gt; MED &gt; PLDD &gt; PELD &gt; CN &gt; APLD. The limitations of this network meta-analysis include the range of study populations and inconformity of the follow-up times and outcome measurements. This meta-analysis provides evidence that PELD might be the best choice to increase the success rate and decrease the complication rate, moreover SOMD might be the best option to drop the reoperation rate. APLD might lead to the lowest success rate and the highest complication and reoperation rate. Higher quality RCTs and direct head to head trials are needed to confirm these results.Key words: Lumbar disc herniation, discectomy, minimally invasive surgery, network meta-analysis.</abstract><cop>United States</cop><pub>American Society of Interventional Pain Physician</pub><pmid>28934804</pmid><oa>free_for_read</oa></addata></record>
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subjects Decompression, Surgical - methods
Decompression, Surgical - standards
Diskectomy - methods
Diskectomy - standards
Diskectomy, Percutaneous - methods
Diskectomy, Percutaneous - standards
Endoscopy - methods
Endoscopy - standards
Humans
Intervertebral Disc - diagnostic imaging
Intervertebral Disc - surgery
Intervertebral Disc Degeneration - diagnostic imaging
Intervertebral Disc Degeneration - surgery
Intervertebral Disc Displacement - diagnostic imaging
Intervertebral Disc Displacement - surgery
Laser discs
Lumbar Vertebrae - diagnostic imaging
Lumbar Vertebrae - surgery
Meta-analysis
Minimally Invasive Surgical Procedures - methods
Minimally Invasive Surgical Procedures - standards
Network Meta-Analysis
Randomized Controlled Trials as Topic - methods
Reoperation - methods
Reoperation - standards
Success
title Comparison of 7 Surgical Interventions for Lumbar Disc Herniation: A Network Meta-analysis
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