Effects of energy supply and nicotinic acid supplementation on phagocytosis and ROS production of blood immune cells of periparturient primi- and pluriparous dairy cows
Effects of energy supply and nicotinic acid (NA) supplementation on the phagocytic activity of polymorphonuclear leukocytes (PMN) and peripheral blood mononuclear cells (PBMC), and on ROS production in PMN of periparturient cows differing in parity were examined. 29 pluriparous and 18 primiparous co...
Gespeichert in:
| Veröffentlicht in: | Research in veterinary science 2018-02, Vol.116, p.62-71 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 71 |
|---|---|
| container_issue | |
| container_start_page | 62 |
| container_title | Research in veterinary science |
| container_volume | 116 |
| creator | Bühler, S. Frahm, J. Liermann, W. Tienken, R. Kersten, S. Meyer, U. Huber, K. Dänicke, S. |
| description | Effects of energy supply and nicotinic acid (NA) supplementation on the phagocytic activity of polymorphonuclear leukocytes (PMN) and peripheral blood mononuclear cells (PBMC), and on ROS production in PMN of periparturient cows differing in parity were examined. 29 pluriparous and 18 primiparous cows were allocated to four different feeding groups from 42days prepartum until 100days postpartum. They were fed either a ration with a low concentrate proportion of 30% (LC) or a high concentrate proportion of 60% (HC). After parturition all animals received 30% concentrate which was increased to 50% either within 16 (LC) or within 24days (HC). The different concentrate feeding strategies aimed at triggering differences in postpartum lipolysis. Half of the animals per group were supplemented with 24g per day of NA from 42days prepartum until 24days postpartum. All investigated parameters varied significantly over time compared to parturition (p |
| doi_str_mv | 10.1016/j.rvsc.2017.09.012 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1942676066</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0034528817306744</els_id><sourcerecordid>2017241418</sourcerecordid><originalsourceid>FETCH-LOGICAL-c384t-2cfc2b70a57f8bf6864c816b82455c358e13608c6051ac062289dcd4323f7b453</originalsourceid><addsrcrecordid>eNp9kc1u1TAQhS0EopfCC7BAltiwSbAdx_GV2KCqUKRKlfhZW87YLr5K4mAnrfJGPCZO0rJggWTZi_nO8cwchF5TUlJCxftTGe8SlIzQpiTHklD2BB1oXbGCCUGfogMhFS9qJuUZepHSiRDCKW2eozMmj1XNSHNAvy-dszAlHBy2g423C07zOHYL1oPBg4cw-XxjDd7sFdvbYdKTDwPOZ_ypbwMsU0g-bZKvN9_wGIOZYUccbrsQDPZ9Pw8Wg-267bPRRj_qOM3RZ78s8b0vNoexm7dSmBM22scFQ7hPL9Ezp7tkXz285-jHp8vvF1fF9c3nLxcfrwuoJJ8KBg5Y2xBdN062TkjBQVLRSsbrGqpaWloJIkGQmmogguVVGDC8YpVrWl5X5-jd7puH-DXbNKnep7VrPdjckaJHzkQjiBAZffsPegpzHHJ3as2EccqpzBTbKYghpWidWmfVcVGUqDVHdVJrjptGkaPKOWbRmwfrue2t-St5DC4DH3bA5l3ceRtVgrxIsMbHnKcywf_P_w_7f7Gn</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2017241418</pqid></control><display><type>article</type><title>Effects of energy supply and nicotinic acid supplementation on phagocytosis and ROS production of blood immune cells of periparturient primi- and pluriparous dairy cows</title><source>Elsevier ScienceDirect Journals Complete</source><creator>Bühler, S. ; Frahm, J. ; Liermann, W. ; Tienken, R. ; Kersten, S. ; Meyer, U. ; Huber, K. ; Dänicke, S.</creator><creatorcontrib>Bühler, S. ; Frahm, J. ; Liermann, W. ; Tienken, R. ; Kersten, S. ; Meyer, U. ; Huber, K. ; Dänicke, S.</creatorcontrib><description>Effects of energy supply and nicotinic acid (NA) supplementation on the phagocytic activity of polymorphonuclear leukocytes (PMN) and peripheral blood mononuclear cells (PBMC), and on ROS production in PMN of periparturient cows differing in parity were examined. 29 pluriparous and 18 primiparous cows were allocated to four different feeding groups from 42days prepartum until 100days postpartum. They were fed either a ration with a low concentrate proportion of 30% (LC) or a high concentrate proportion of 60% (HC). After parturition all animals received 30% concentrate which was increased to 50% either within 16 (LC) or within 24days (HC). The different concentrate feeding strategies aimed at triggering differences in postpartum lipolysis. Half of the animals per group were supplemented with 24g per day of NA from 42days prepartum until 24days postpartum. All investigated parameters varied significantly over time compared to parturition (p<0.05). Numbers of phagocytosing PMN and PBMC increased in the course of the experiment, whereas the amount of engulfed bacteria per cell decreased between 42 and 11days prepartum. Percentage of basal ROS producing PMN decreased strongly before parturition and reached initial values only at 28days in milk again. Mean fluorescence intensity (MFI) in these ROS producing cells, however, increased before parturition. Oxidative burst stimulation in PMN was reduced around parturition but the amount of ROS produced in the stimulated cells was increased. Pluriparous cows exhibited higher numbers of basal ROS producing PMN and phagocytic PBMC. NA supplementation influenced phagocytosis in blood leukocytes.
•Time courses of phagocytic activity of PMN and PBMC and ROS production in PMN throughout the periparturient period.•Comparison of the functional capacity of blood leukocytes between primi- and pluriparous cows.•Functional activity of blood leukocytes is significantly influenced by parturition but not only impaired.</description><identifier>ISSN: 0034-5288</identifier><identifier>EISSN: 1532-2661</identifier><identifier>DOI: 10.1016/j.rvsc.2017.09.012</identifier><identifier>PMID: 28935207</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adenosine ; Animal lactation ; Animals ; Cattle ; Dairy cattle ; Diet ; Energy ; Experiments ; Fatty acids ; Feeding ; Flow cytometry ; Fluorescence ; Immune system ; Immunology ; Leukocytes ; Leukocytes (mononuclear) ; Leukocytes (polymorphonuclear) ; Lipolysis ; Metabolism ; Neutrophils ; Niacin ; Nicotinic acid ; Oxidative burst ; Oxidative stress ; Parturition ; Peripheral blood mononuclear cells ; Peripheral blood mononuclear cells (PBMC) ; Phagocytes ; Phagocytosis ; Polymorphonuclear leukocytes (PMN) ; Postpartum ; Supplements ; Transition period ; Veterinary medicine ; Vitamin B</subject><ispartof>Research in veterinary science, 2018-02, Vol.116, p.62-71</ispartof><rights>2017 Elsevier Ltd</rights><rights>Copyright © 2017 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Feb 1, 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-2cfc2b70a57f8bf6864c816b82455c358e13608c6051ac062289dcd4323f7b453</citedby><cites>FETCH-LOGICAL-c384t-2cfc2b70a57f8bf6864c816b82455c358e13608c6051ac062289dcd4323f7b453</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.rvsc.2017.09.012$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28935207$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bühler, S.</creatorcontrib><creatorcontrib>Frahm, J.</creatorcontrib><creatorcontrib>Liermann, W.</creatorcontrib><creatorcontrib>Tienken, R.</creatorcontrib><creatorcontrib>Kersten, S.</creatorcontrib><creatorcontrib>Meyer, U.</creatorcontrib><creatorcontrib>Huber, K.</creatorcontrib><creatorcontrib>Dänicke, S.</creatorcontrib><title>Effects of energy supply and nicotinic acid supplementation on phagocytosis and ROS production of blood immune cells of periparturient primi- and pluriparous dairy cows</title><title>Research in veterinary science</title><addtitle>Res Vet Sci</addtitle><description>Effects of energy supply and nicotinic acid (NA) supplementation on the phagocytic activity of polymorphonuclear leukocytes (PMN) and peripheral blood mononuclear cells (PBMC), and on ROS production in PMN of periparturient cows differing in parity were examined. 29 pluriparous and 18 primiparous cows were allocated to four different feeding groups from 42days prepartum until 100days postpartum. They were fed either a ration with a low concentrate proportion of 30% (LC) or a high concentrate proportion of 60% (HC). After parturition all animals received 30% concentrate which was increased to 50% either within 16 (LC) or within 24days (HC). The different concentrate feeding strategies aimed at triggering differences in postpartum lipolysis. Half of the animals per group were supplemented with 24g per day of NA from 42days prepartum until 24days postpartum. All investigated parameters varied significantly over time compared to parturition (p<0.05). Numbers of phagocytosing PMN and PBMC increased in the course of the experiment, whereas the amount of engulfed bacteria per cell decreased between 42 and 11days prepartum. Percentage of basal ROS producing PMN decreased strongly before parturition and reached initial values only at 28days in milk again. Mean fluorescence intensity (MFI) in these ROS producing cells, however, increased before parturition. Oxidative burst stimulation in PMN was reduced around parturition but the amount of ROS produced in the stimulated cells was increased. Pluriparous cows exhibited higher numbers of basal ROS producing PMN and phagocytic PBMC. NA supplementation influenced phagocytosis in blood leukocytes.
•Time courses of phagocytic activity of PMN and PBMC and ROS production in PMN throughout the periparturient period.•Comparison of the functional capacity of blood leukocytes between primi- and pluriparous cows.•Functional activity of blood leukocytes is significantly influenced by parturition but not only impaired.</description><subject>Adenosine</subject><subject>Animal lactation</subject><subject>Animals</subject><subject>Cattle</subject><subject>Dairy cattle</subject><subject>Diet</subject><subject>Energy</subject><subject>Experiments</subject><subject>Fatty acids</subject><subject>Feeding</subject><subject>Flow cytometry</subject><subject>Fluorescence</subject><subject>Immune system</subject><subject>Immunology</subject><subject>Leukocytes</subject><subject>Leukocytes (mononuclear)</subject><subject>Leukocytes (polymorphonuclear)</subject><subject>Lipolysis</subject><subject>Metabolism</subject><subject>Neutrophils</subject><subject>Niacin</subject><subject>Nicotinic acid</subject><subject>Oxidative burst</subject><subject>Oxidative stress</subject><subject>Parturition</subject><subject>Peripheral blood mononuclear cells</subject><subject>Peripheral blood mononuclear cells (PBMC)</subject><subject>Phagocytes</subject><subject>Phagocytosis</subject><subject>Polymorphonuclear leukocytes (PMN)</subject><subject>Postpartum</subject><subject>Supplements</subject><subject>Transition period</subject><subject>Veterinary medicine</subject><subject>Vitamin B</subject><issn>0034-5288</issn><issn>1532-2661</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kc1u1TAQhS0EopfCC7BAltiwSbAdx_GV2KCqUKRKlfhZW87YLr5K4mAnrfJGPCZO0rJggWTZi_nO8cwchF5TUlJCxftTGe8SlIzQpiTHklD2BB1oXbGCCUGfogMhFS9qJuUZepHSiRDCKW2eozMmj1XNSHNAvy-dszAlHBy2g423C07zOHYL1oPBg4cw-XxjDd7sFdvbYdKTDwPOZ_ypbwMsU0g-bZKvN9_wGIOZYUccbrsQDPZ9Pw8Wg-267bPRRj_qOM3RZ78s8b0vNoexm7dSmBM22scFQ7hPL9Ezp7tkXz285-jHp8vvF1fF9c3nLxcfrwuoJJ8KBg5Y2xBdN062TkjBQVLRSsbrGqpaWloJIkGQmmogguVVGDC8YpVrWl5X5-jd7puH-DXbNKnep7VrPdjckaJHzkQjiBAZffsPegpzHHJ3as2EccqpzBTbKYghpWidWmfVcVGUqDVHdVJrjptGkaPKOWbRmwfrue2t-St5DC4DH3bA5l3ceRtVgrxIsMbHnKcywf_P_w_7f7Gn</recordid><startdate>201802</startdate><enddate>201802</enddate><creator>Bühler, S.</creator><creator>Frahm, J.</creator><creator>Liermann, W.</creator><creator>Tienken, R.</creator><creator>Kersten, S.</creator><creator>Meyer, U.</creator><creator>Huber, K.</creator><creator>Dänicke, S.</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QP</scope><scope>7QR</scope><scope>7T5</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>201802</creationdate><title>Effects of energy supply and nicotinic acid supplementation on phagocytosis and ROS production of blood immune cells of periparturient primi- and pluriparous dairy cows</title><author>Bühler, S. ; Frahm, J. ; Liermann, W. ; Tienken, R. ; Kersten, S. ; Meyer, U. ; Huber, K. ; Dänicke, S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-2cfc2b70a57f8bf6864c816b82455c358e13608c6051ac062289dcd4323f7b453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adenosine</topic><topic>Animal lactation</topic><topic>Animals</topic><topic>Cattle</topic><topic>Dairy cattle</topic><topic>Diet</topic><topic>Energy</topic><topic>Experiments</topic><topic>Fatty acids</topic><topic>Feeding</topic><topic>Flow cytometry</topic><topic>Fluorescence</topic><topic>Immune system</topic><topic>Immunology</topic><topic>Leukocytes</topic><topic>Leukocytes (mononuclear)</topic><topic>Leukocytes (polymorphonuclear)</topic><topic>Lipolysis</topic><topic>Metabolism</topic><topic>Neutrophils</topic><topic>Niacin</topic><topic>Nicotinic acid</topic><topic>Oxidative burst</topic><topic>Oxidative stress</topic><topic>Parturition</topic><topic>Peripheral blood mononuclear cells</topic><topic>Peripheral blood mononuclear cells (PBMC)</topic><topic>Phagocytes</topic><topic>Phagocytosis</topic><topic>Polymorphonuclear leukocytes (PMN)</topic><topic>Postpartum</topic><topic>Supplements</topic><topic>Transition period</topic><topic>Veterinary medicine</topic><topic>Vitamin B</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bühler, S.</creatorcontrib><creatorcontrib>Frahm, J.</creatorcontrib><creatorcontrib>Liermann, W.</creatorcontrib><creatorcontrib>Tienken, R.</creatorcontrib><creatorcontrib>Kersten, S.</creatorcontrib><creatorcontrib>Meyer, U.</creatorcontrib><creatorcontrib>Huber, K.</creatorcontrib><creatorcontrib>Dänicke, S.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Research in veterinary science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bühler, S.</au><au>Frahm, J.</au><au>Liermann, W.</au><au>Tienken, R.</au><au>Kersten, S.</au><au>Meyer, U.</au><au>Huber, K.</au><au>Dänicke, S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of energy supply and nicotinic acid supplementation on phagocytosis and ROS production of blood immune cells of periparturient primi- and pluriparous dairy cows</atitle><jtitle>Research in veterinary science</jtitle><addtitle>Res Vet Sci</addtitle><date>2018-02</date><risdate>2018</risdate><volume>116</volume><spage>62</spage><epage>71</epage><pages>62-71</pages><issn>0034-5288</issn><eissn>1532-2661</eissn><abstract>Effects of energy supply and nicotinic acid (NA) supplementation on the phagocytic activity of polymorphonuclear leukocytes (PMN) and peripheral blood mononuclear cells (PBMC), and on ROS production in PMN of periparturient cows differing in parity were examined. 29 pluriparous and 18 primiparous cows were allocated to four different feeding groups from 42days prepartum until 100days postpartum. They were fed either a ration with a low concentrate proportion of 30% (LC) or a high concentrate proportion of 60% (HC). After parturition all animals received 30% concentrate which was increased to 50% either within 16 (LC) or within 24days (HC). The different concentrate feeding strategies aimed at triggering differences in postpartum lipolysis. Half of the animals per group were supplemented with 24g per day of NA from 42days prepartum until 24days postpartum. All investigated parameters varied significantly over time compared to parturition (p<0.05). Numbers of phagocytosing PMN and PBMC increased in the course of the experiment, whereas the amount of engulfed bacteria per cell decreased between 42 and 11days prepartum. Percentage of basal ROS producing PMN decreased strongly before parturition and reached initial values only at 28days in milk again. Mean fluorescence intensity (MFI) in these ROS producing cells, however, increased before parturition. Oxidative burst stimulation in PMN was reduced around parturition but the amount of ROS produced in the stimulated cells was increased. Pluriparous cows exhibited higher numbers of basal ROS producing PMN and phagocytic PBMC. NA supplementation influenced phagocytosis in blood leukocytes.
•Time courses of phagocytic activity of PMN and PBMC and ROS production in PMN throughout the periparturient period.•Comparison of the functional capacity of blood leukocytes between primi- and pluriparous cows.•Functional activity of blood leukocytes is significantly influenced by parturition but not only impaired.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>28935207</pmid><doi>10.1016/j.rvsc.2017.09.012</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0034-5288 |
| ispartof | Research in veterinary science, 2018-02, Vol.116, p.62-71 |
| issn | 0034-5288 1532-2661 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1942676066 |
| source | Elsevier ScienceDirect Journals Complete |
| subjects | Adenosine Animal lactation Animals Cattle Dairy cattle Diet Energy Experiments Fatty acids Feeding Flow cytometry Fluorescence Immune system Immunology Leukocytes Leukocytes (mononuclear) Leukocytes (polymorphonuclear) Lipolysis Metabolism Neutrophils Niacin Nicotinic acid Oxidative burst Oxidative stress Parturition Peripheral blood mononuclear cells Peripheral blood mononuclear cells (PBMC) Phagocytes Phagocytosis Polymorphonuclear leukocytes (PMN) Postpartum Supplements Transition period Veterinary medicine Vitamin B |
| title | Effects of energy supply and nicotinic acid supplementation on phagocytosis and ROS production of blood immune cells of periparturient primi- and pluriparous dairy cows |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T06%3A48%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20energy%20supply%20and%20nicotinic%20acid%20supplementation%20on%20phagocytosis%20and%20ROS%20production%20of%20blood%20immune%20cells%20of%20periparturient%20primi-%20and%20pluriparous%20dairy%20cows&rft.jtitle=Research%20in%20veterinary%20science&rft.au=B%C3%BChler,%20S.&rft.date=2018-02&rft.volume=116&rft.spage=62&rft.epage=71&rft.pages=62-71&rft.issn=0034-5288&rft.eissn=1532-2661&rft_id=info:doi/10.1016/j.rvsc.2017.09.012&rft_dat=%3Cproquest_cross%3E2017241418%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2017241418&rft_id=info:pmid/28935207&rft_els_id=S0034528817306744&rfr_iscdi=true |