Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients
Purpose Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters. Results Forty-five...
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| Veröffentlicht in: | Digestive diseases and sciences 2014-12, Vol.59 (12), p.3004-3011 |
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| creator | Cincin, Altug Sunbul, Murat Kivrak, Tarık Atas, Halil Sari, Ibrahim Tigen, Kursat Kani, Tarik Akin, Hakan Imeryuz, Nese Basaran, Yelda |
| description | Purpose
Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters.
Results
Forty-five UC patients (mean age 37, 18 female) and 90 age- and sex-matched healthy volunteers (mean age 40, 38 female) included in the study. The mean disease activity score according to partial Mayo score was 2.16 ± 2.13. Mean global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) measurements were significantly lower (−21.16 ± 2.71 vs. −23.36 ± 3.34;
p
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| doi_str_mv | 10.1007/s10620-014-3274-4 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1942221246</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A712944168</galeid><sourcerecordid>A712944168</sourcerecordid><originalsourceid>FETCH-LOGICAL-c472t-ba440b8b88077bc1a7d4a404547a9cd12f4b9062b076f35952b61cf0023e2f5a3</originalsourceid><addsrcrecordid>eNqFkktv3CAUhVHVqJmk_QHdVEjddOMErjHYy2gyaSpFSqRO1ghjPCHBMAU71fz74kz6VKsKicflO0dcdBB6S8kJJUScJko4kIJQVpQgWMFeoAWtRFlAxeuXaEEoz3tK-SE6SumeENIIyl-hQ6gIlABigeLqUblJjTZ4HHq8VLGzSuOLyeunWrvD66-hOLeD8SkXlMOft0Y_OIPXUekH6zd4pe-CnoVhE9X2boetx7dOm5htHw1eBmdHm_BNPho_ptfooFcumTfP6zG6vVitl5fF1fXHT8uzq0IzAWPRKsZIW7d1TYRoNVWiY4oRVjGhGt1R6Fnb5P5bInhfVk0FLae6J7kzA32lymP0Ye-7jeHLZNIoB5u0cU55E6YkacMAgALj_0c5CCIaEDP6_g_0Pkwx_8sTVdV5guontVHOSOv7MObfmk3lmaDQMEZ5namTv1B5dGawOnjT21z_TUD3Ah1DStH0chvtoOJOUiLnSMh9JGSOhJwjIVnWvHt-8NQOpvuh-J6BDMAeSPnKb0z8paN_un4Dj8u-kA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1625816225</pqid></control><display><type>article</type><title>Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Cincin, Altug ; Sunbul, Murat ; Kivrak, Tarık ; Atas, Halil ; Sari, Ibrahim ; Tigen, Kursat ; Kani, Tarik ; Akin, Hakan ; Imeryuz, Nese ; Basaran, Yelda</creator><creatorcontrib>Cincin, Altug ; Sunbul, Murat ; Kivrak, Tarık ; Atas, Halil ; Sari, Ibrahim ; Tigen, Kursat ; Kani, Tarik ; Akin, Hakan ; Imeryuz, Nese ; Basaran, Yelda</creatorcontrib><description>Purpose
Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters.
Results
Forty-five UC patients (mean age 37, 18 female) and 90 age- and sex-matched healthy volunteers (mean age 40, 38 female) included in the study. The mean disease activity score according to partial Mayo score was 2.16 ± 2.13. Mean global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) measurements were significantly lower (−21.16 ± 2.71 vs. −23.36 ± 3.34;
p
< 0.001 and −1.33 ± 0.24 vs. −1.43 ± 0.24;
p
= 0.037, respectively), whereas global circumferential (−22.67 ± 3.66 vs. −23.37 ± 3.99;
p
= 0.140) and global radial strain (43.07 ± 8.58 vs. 44.12 ± 9.32;
p
= 0.545) measurements of the LV were similar in patients with UC compared with controls. The correlation coefficient (
r
) between GLS and partial Mayo score was −0.578 (
p
< 0.001).
Conclusion
Our study suggests that systolic cardiac deformation values are impaired in UC patients. Reduced GLS and GLSR might be an early indicator of cardiac involvement in this population.</description><identifier>ISSN: 0163-2116</identifier><identifier>EISSN: 1573-2568</identifier><identifier>DOI: 10.1007/s10620-014-3274-4</identifier><identifier>PMID: 25023227</identifier><identifier>CODEN: DDSCDJ</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Adalimumab ; Adult ; Analysis ; Biochemistry ; Case-Control Studies ; Colitis, Ulcerative - complications ; Echocardiography ; Echocardiography - methods ; Female ; Gastroenterology ; Heart ; Hepatology ; Humans ; Male ; Medical research ; Medicine ; Medicine & Public Health ; Medicine, Experimental ; Middle Aged ; Oncology ; Original Article ; Transplant Surgery ; Ulcerative colitis ; Ventricular Function, Left - physiology ; Young Adult</subject><ispartof>Digestive diseases and sciences, 2014-12, Vol.59 (12), p.3004-3011</ispartof><rights>Springer Science+Business Media New York 2014</rights><rights>COPYRIGHT 2014 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-ba440b8b88077bc1a7d4a404547a9cd12f4b9062b076f35952b61cf0023e2f5a3</citedby><cites>FETCH-LOGICAL-c472t-ba440b8b88077bc1a7d4a404547a9cd12f4b9062b076f35952b61cf0023e2f5a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10620-014-3274-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10620-014-3274-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25023227$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cincin, Altug</creatorcontrib><creatorcontrib>Sunbul, Murat</creatorcontrib><creatorcontrib>Kivrak, Tarık</creatorcontrib><creatorcontrib>Atas, Halil</creatorcontrib><creatorcontrib>Sari, Ibrahim</creatorcontrib><creatorcontrib>Tigen, Kursat</creatorcontrib><creatorcontrib>Kani, Tarik</creatorcontrib><creatorcontrib>Akin, Hakan</creatorcontrib><creatorcontrib>Imeryuz, Nese</creatorcontrib><creatorcontrib>Basaran, Yelda</creatorcontrib><title>Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients</title><title>Digestive diseases and sciences</title><addtitle>Dig Dis Sci</addtitle><addtitle>Dig Dis Sci</addtitle><description>Purpose
Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters.
Results
Forty-five UC patients (mean age 37, 18 female) and 90 age- and sex-matched healthy volunteers (mean age 40, 38 female) included in the study. The mean disease activity score according to partial Mayo score was 2.16 ± 2.13. Mean global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) measurements were significantly lower (−21.16 ± 2.71 vs. −23.36 ± 3.34;
p
< 0.001 and −1.33 ± 0.24 vs. −1.43 ± 0.24;
p
= 0.037, respectively), whereas global circumferential (−22.67 ± 3.66 vs. −23.37 ± 3.99;
p
= 0.140) and global radial strain (43.07 ± 8.58 vs. 44.12 ± 9.32;
p
= 0.545) measurements of the LV were similar in patients with UC compared with controls. The correlation coefficient (
r
) between GLS and partial Mayo score was −0.578 (
p
< 0.001).
Conclusion
Our study suggests that systolic cardiac deformation values are impaired in UC patients. Reduced GLS and GLSR might be an early indicator of cardiac involvement in this population.</description><subject>Adalimumab</subject><subject>Adult</subject><subject>Analysis</subject><subject>Biochemistry</subject><subject>Case-Control Studies</subject><subject>Colitis, Ulcerative - complications</subject><subject>Echocardiography</subject><subject>Echocardiography - methods</subject><subject>Female</subject><subject>Gastroenterology</subject><subject>Heart</subject><subject>Hepatology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Transplant Surgery</subject><subject>Ulcerative colitis</subject><subject>Ventricular Function, Left - physiology</subject><subject>Young Adult</subject><issn>0163-2116</issn><issn>1573-2568</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFkktv3CAUhVHVqJmk_QHdVEjddOMErjHYy2gyaSpFSqRO1ghjPCHBMAU71fz74kz6VKsKicflO0dcdBB6S8kJJUScJko4kIJQVpQgWMFeoAWtRFlAxeuXaEEoz3tK-SE6SumeENIIyl-hQ6gIlABigeLqUblJjTZ4HHq8VLGzSuOLyeunWrvD66-hOLeD8SkXlMOft0Y_OIPXUekH6zd4pe-CnoVhE9X2boetx7dOm5htHw1eBmdHm_BNPho_ptfooFcumTfP6zG6vVitl5fF1fXHT8uzq0IzAWPRKsZIW7d1TYRoNVWiY4oRVjGhGt1R6Fnb5P5bInhfVk0FLae6J7kzA32lymP0Ye-7jeHLZNIoB5u0cU55E6YkacMAgALj_0c5CCIaEDP6_g_0Pkwx_8sTVdV5guontVHOSOv7MObfmk3lmaDQMEZ5namTv1B5dGawOnjT21z_TUD3Ah1DStH0chvtoOJOUiLnSMh9JGSOhJwjIVnWvHt-8NQOpvuh-J6BDMAeSPnKb0z8paN_un4Dj8u-kA</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Cincin, Altug</creator><creator>Sunbul, Murat</creator><creator>Kivrak, Tarık</creator><creator>Atas, Halil</creator><creator>Sari, Ibrahim</creator><creator>Tigen, Kursat</creator><creator>Kani, Tarik</creator><creator>Akin, Hakan</creator><creator>Imeryuz, Nese</creator><creator>Basaran, Yelda</creator><general>Springer US</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>20141201</creationdate><title>Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients</title><author>Cincin, Altug ; Sunbul, Murat ; Kivrak, Tarık ; Atas, Halil ; Sari, Ibrahim ; Tigen, Kursat ; Kani, Tarik ; Akin, Hakan ; Imeryuz, Nese ; Basaran, Yelda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-ba440b8b88077bc1a7d4a404547a9cd12f4b9062b076f35952b61cf0023e2f5a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adalimumab</topic><topic>Adult</topic><topic>Analysis</topic><topic>Biochemistry</topic><topic>Case-Control Studies</topic><topic>Colitis, Ulcerative - complications</topic><topic>Echocardiography</topic><topic>Echocardiography - methods</topic><topic>Female</topic><topic>Gastroenterology</topic><topic>Heart</topic><topic>Hepatology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Transplant Surgery</topic><topic>Ulcerative colitis</topic><topic>Ventricular Function, Left - physiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cincin, Altug</creatorcontrib><creatorcontrib>Sunbul, Murat</creatorcontrib><creatorcontrib>Kivrak, Tarık</creatorcontrib><creatorcontrib>Atas, Halil</creatorcontrib><creatorcontrib>Sari, Ibrahim</creatorcontrib><creatorcontrib>Tigen, Kursat</creatorcontrib><creatorcontrib>Kani, Tarik</creatorcontrib><creatorcontrib>Akin, Hakan</creatorcontrib><creatorcontrib>Imeryuz, Nese</creatorcontrib><creatorcontrib>Basaran, Yelda</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Digestive diseases and sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cincin, Altug</au><au>Sunbul, Murat</au><au>Kivrak, Tarık</au><au>Atas, Halil</au><au>Sari, Ibrahim</au><au>Tigen, Kursat</au><au>Kani, Tarik</au><au>Akin, Hakan</au><au>Imeryuz, Nese</au><au>Basaran, Yelda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients</atitle><jtitle>Digestive diseases and sciences</jtitle><stitle>Dig Dis Sci</stitle><addtitle>Dig Dis Sci</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>59</volume><issue>12</issue><spage>3004</spage><epage>3011</epage><pages>3004-3011</pages><issn>0163-2116</issn><eissn>1573-2568</eissn><coden>DDSCDJ</coden><abstract>Purpose
Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters.
Results
Forty-five UC patients (mean age 37, 18 female) and 90 age- and sex-matched healthy volunteers (mean age 40, 38 female) included in the study. The mean disease activity score according to partial Mayo score was 2.16 ± 2.13. Mean global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) measurements were significantly lower (−21.16 ± 2.71 vs. −23.36 ± 3.34;
p
< 0.001 and −1.33 ± 0.24 vs. −1.43 ± 0.24;
p
= 0.037, respectively), whereas global circumferential (−22.67 ± 3.66 vs. −23.37 ± 3.99;
p
= 0.140) and global radial strain (43.07 ± 8.58 vs. 44.12 ± 9.32;
p
= 0.545) measurements of the LV were similar in patients with UC compared with controls. The correlation coefficient (
r
) between GLS and partial Mayo score was −0.578 (
p
< 0.001).
Conclusion
Our study suggests that systolic cardiac deformation values are impaired in UC patients. Reduced GLS and GLSR might be an early indicator of cardiac involvement in this population.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>25023227</pmid><doi>10.1007/s10620-014-3274-4</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0163-2116 |
| ispartof | Digestive diseases and sciences, 2014-12, Vol.59 (12), p.3004-3011 |
| issn | 0163-2116 1573-2568 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adalimumab Adult Analysis Biochemistry Case-Control Studies Colitis, Ulcerative - complications Echocardiography Echocardiography - methods Female Gastroenterology Heart Hepatology Humans Male Medical research Medicine Medicine & Public Health Medicine, Experimental Middle Aged Oncology Original Article Transplant Surgery Ulcerative colitis Ventricular Function, Left - physiology Young Adult |
| title | Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients |
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