Thymoquinone Prevents and Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice

Background Thymoquinone (TQ), an active ingredient of the seed oil extract of Nigella sativa Linn, has previously been shown to possess antitumor, antioxidant, and anti-inflammatory bioactivity. Whether TQ has any effect on colitis remains controversial. Aim The aim of this study was to determine wh...

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Veröffentlicht in:	Digestive diseases and sciences 2012-09, Vol.57 (9), p.2296-2303
Hauptverfasser:	Lei, Xiaofei, Liu, Meng, Yang, Zirong, Ji, Mengyao, Guo, Xufeng, Dong, Weiguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - pharmacology Antioxidants Benzoquinones - chemistry Benzoquinones - pharmacology Biochemistry Colitis Colitis - chemically induced Colitis - pathology Colitis - prevention & control Dextran Dextran Sulfate - toxicity Drinking water Female Gastroenterology Glutathione Hepatology Inflammation Malondialdehyde Medicine Medicine & Public Health Mice Mice, Inbred C57BL Nigella sativa Nigella sativa - chemistry Oncology Original Article Peroxidase Plant Oils - chemistry Pneumoviridae Prevention Seeds - chemistry Sulfates Time Factors Transplant Surgery Water-supply
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