Orally administered marine (1 → 3)-β- d-glucan Phycarine stimulates both humoral and cellular immunity

(1 → 3)-β- d-Glucans represent highly conserved structural components of cell walls in yeast, fungi, or seaweed. However, it is still unknown how they mediate their effects. The aim of this study was to evaluate both intraperitoneal and oral application of seaweed-derived (1 → 3)-β- d-glucan Phycari...

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Veröffentlicht in:	International journal of biological macromolecules 2007-03, Vol.40 (4), p.291-298
Hauptverfasser:	Vetvicka, Vaclav, Dvorak, Bohuslav, Vetvickova, Jana, Richter, Jan, Krizan, Jiri, Sima, Petr, Yvin, Jean-Claude
Format:	Artikel
Sprache:	eng
Schlagworte:	(1 → 3)-β- d-Glucan Administration, Oral Animals Antibody Formation - drug effects Antibody Formation - radiation effects Apoptosis - drug effects Apoptosis - radiation effects beta-Glucans - administration & dosage beta-Glucans - pharmacokinetics beta-Glucans - pharmacology beta-Glucans - therapeutic use Bone Marrow Cells - cytology Bone Marrow Cells - drug effects Bone Marrow Cells - radiation effects Cancer Carcinoma, Lewis Lung - chemically induced Carcinoma, Lewis Lung - drug therapy Carcinoma, Lewis Lung - pathology Cell Count Cyclophosphamide - pharmacology Immunity Immunity, Cellular - drug effects Immunity, Cellular - radiation effects Injections, Intraperitoneal Iodine Radioisotopes Killer Cells, Natural - drug effects Killer Cells, Natural - immunology Killer Cells, Natural - radiation effects Leukopenia - chemically induced Mice Mice, Inbred BALB C Microspheres Phagocytosis Phagocytosis - drug effects Phagocytosis - radiation effects Rats Rats, Sprague-Dawley Seaweed - metabolism Spleen - cytology Spleen - drug effects Spleen - radiation effects Thymus Gland - cytology Thymus Gland - drug effects Thymus Gland - radiation effects Tissue Distribution - drug effects
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