Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques

The main goal of a novel drug development is to obtain it with optimal physiochemical, pharmaceutical and biological properties. Pharmaceutical companies and scientists modify active pharmaceutical ingredients (APIs), which often are cocrystals, salts or carefully selected polymorphs, to improve the...

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Veröffentlicht in:	Advanced drug delivery reviews 2017-08, Vol.117, p.111-146
Hauptverfasser:	Pindelska, Edyta, Sokal, Agnieszka, Kolodziejski, Waclaw
Format:	Artikel
Sprache:	eng
Schlagworte:	Active pharmaceutical ingredient Calorimetry, Differential Scanning Crystallization Crystallographic studies Drug Molecular Structure NMR crystallography Pharmaceutical Preparations - analysis Pharmaceutical Preparations - chemistry Salts Solubility Spectroscopic characterization Stability Thermal analysis Thermogravimetry
Online-Zugang:	Volltext
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