Cerebrovascular reactivity measurement in cerebral small vessel disease: Rationale and reproducibility of a protocol for MRI acquisition and image processing

Background Impaired autoregulation may contribute to the pathogenesis of cerebral small vessel disease. Reliable protocols for measuring microvascular reactivity are required to test this hypothesis and for providing secondary endpoints in clinical trials. Aims To develop and assess a protocol for a...

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Veröffentlicht in:	International journal of stroke 2018-02, Vol.13 (2), p.195-206
Hauptverfasser:	Thrippleton, Michael J, Shi, Yulu, Blair, Gordon, Hamilton, Iona, Waiter, Gordon, Schwarzbauer, Christian, Pernet, Cyril, Andrews, Peter JD, Marshall, Ian, Doubal, Fergus, Wardlaw, Joanna M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cerebral Small Vessel Diseases - diagnosis Cerebrovascular Circulation Female Gray Matter - blood supply Gray Matter - diagnostic imaging Healthy Volunteers Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging - methods Male Microvessels - diagnostic imaging Microvessels - pathology Middle Aged Reproducibility of Results Stroke - diagnosis White Matter - blood supply White Matter - diagnostic imaging Young Adult
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