Analyzing polymeric matrix for fabrication of a biodegradable microneedle array to enhance transdermal delivery

Traditional drug delivery systems, using invasive, transdermal, and oral routes, are limited by various factors, such as the digestive system environment, skin protection, and sensory nerve stimulation. To improve the drug delivery system, we fabricated a polysaccharide-based, dissolvable microneedl...

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Veröffentlicht in:	Biomedical microdevices 2017-12, Vol.19 (4), p.84-13, Article 84
Hauptverfasser:	Hwa, Kuo-Yuan, Chang, Vincent H. S., Cheng, Yao-Yi, Wang, Yue-Da, Jan, Pey-Shynan, Subramani, Boopathi, Wu, Min-Ju, Wang, Bo-Kai
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Aluminum Animal research Animals Biocompatibility Biodegradability Biodegradable Plastics Biodegradation Biological and Medical Physics Biomedical Engineering and Bioengineering Biophysics Cytotoxicity Digestive system Drug delivery Drug delivery systems Engineering Engineering Fluid Dynamics Fabrication Feedback Low temperature Materials Testing Mice Mice, Inbred BALB C Mice, Nude Nanotechnology Needles NIH 3T3 Cells Physical properties Polysaccharides Saccharides Skin Toxicity testing Transdermal medication Vacuum Vacuum deposition
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