Effects of β-naphthoflavone on hepatic biotransformation and glutathione biosynthesis in largemouth bass ( Micropterus salmoides)

We are investigating the effects of in vivo exposure of prototypical enzyme inducing agents on hepatic biotransformation enzyme expression in largemouth bass ( Micropterus salmoides), a predatory game fish found throughout the United States and Canada. The current study targeted those genes involved...

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Veröffentlicht in:	Marine environmental research 2004-08, Vol.58 (2), p.675-679
Hauptverfasser:	Hughes, Erin M., Gallagher, Evan P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Androstenedione Animal and plant ecology Animal, plant and microbial ecology Animals Bass - metabolism beta-Naphthoflavone - pharmacokinetics beta-Naphthoflavone - toxicity Biological and medical sciences Biotransformation - drug effects Cytochrome P-450 CYP1A1 - biosynthesis Dinitrochlorobenzene DNA Primers DNA, Complementary - genetics Enzyme Induction - drug effects Freshwater Fundamental and applied biological sciences. Psychology Glutamate-Cysteine Ligase - biosynthesis Glutamate-Cysteine Ligase - genetics Glutathione Glutathione - metabolism Glutathione S-transferases Glutathione Transferase - biosynthesis Glutathione Transferase - genetics Largemouth bass Liver - enzymology Micropterus salmoides Microsomes - enzymology mRNA Plasmids - genetics Polymerase Chain Reaction - methods RNA, Messenger - metabolism Sea water ecosystems Synecology β-Naphthoflavone
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