Personalized translational epilepsy research - Novel approaches and future perspectives: Part I: Clinical and network analysis approaches

Despite the availability of more than 15 new "antiepileptic drugs", the proportion of patients with pharmacoresistant epilepsy has remained constant at about 20-30%. Furthermore, no disease-modifying treatments shown to prevent the development of epilepsy following an initial precipitating...

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Veröffentlicht in:	Epilepsy & behavior 2017-11, Vol.76, p.13-18
Hauptverfasser:	Rosenow, Felix, van Alphen, Natascha, Becker, Albert, Chiocchetti, Andreas, Deichmann, Ralf, Deller, Thomas, Freiman, Thomas, Freitag, Christine M, Gehrig, Johannes, Hermsen, Anke M, Jedlicka, Peter, Kell, Christian, Klein, Karl Martin, Knake, Susanne, Kullmann, Dimitri M, Liebner, Stefan, Norwood, Braxton A, Omigie, Diana, Plate, Karlheinz, Reif, Andreas, Reif, Philipp S, Reiss, Yvonne, Roeper, Jochen, Ronellenfitsch, Michael W, Schorge, Stephanie, Schratt, Gerhard, Schwarzacher, Stephan W, Steinbach, Joachim P, Strzelczyk, Adam, Triesch, Jochen, Wagner, Marlies, Walker, Matthew C, von Wegner, Frederic, Bauer, Sebastian
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - therapeutic use Blood-Brain Barrier Brain - pathology Brain Injuries - pathology Epigenomics Epilepsy - drug therapy Epilepsy - genetics Genetic Markers - genetics Genetic Variation Humans Precision Medicine - trends Translational Medical Research Treatment Outcome
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