Coupling of translation initiation and termination does not depend on the mode of initiation

Recently we described a novel phenomenon observed during eukaryotic translation in a cell-free system: the coupling of initiation and termination on different mRNA molecules. Here we show that the phenomenon does not depend on a special mode of initiation. The mRNAs with certain leader sequences kno...

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Veröffentlicht in:	Biochemistry (Moscow) 2017-07, Vol.82 (7), p.816-820
Hauptverfasser:	Sogorin, E. A., Selikhanov, G. K., Agalarov, S. Ch
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Cell-free system Cell-Free System - metabolism Coupling (molecular) Eukaryotic Initiation Factor-2 - antagonists & inhibitors Eukaryotic Initiation Factor-2 - metabolism Eukaryotic Initiation Factor-4A - antagonists & inhibitors Eukaryotic Initiation Factor-4A - metabolism Genes, Reporter Genetic research Initiation factors Internal ribosome entry site Internal Ribosome Entry Sites - genetics Life Sciences Messenger RNA Microbiology Nucleotide sequence Paralysis Peptide Chain Initiation, Translational Peptide Chain Termination, Translational Plasmids - metabolism Ribonucleic acid RNA RNA viruses RNA, Messenger - metabolism Scanning Sterols - chemistry Sterols - metabolism Transfer RNA Translation (Genetics) Translation initiation Translation termination tRNA Viruses
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