Binding mode of metal ions to the bacterial iron import protein EfeO

The tripartite EfeUOB system functions as a low pH iron importer in Gram-negative bacteria. In the alginate-assimilating bacterium Sphingomonas sp. strain A1, an additional EfeO-like protein (Algp7) is encoded downstream of the efeUOB operon. Here we show the metal binding mode of Algp7, which carri...

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Veröffentlicht in:	Biochemical and biophysical research communications 2017-11, Vol.493 (2), p.1095-1101
Hauptverfasser:	Temtrirath, Kanate, Okumura, Kenji, Maruyama, Yukie, Mikami, Bunzo, Murata, Kousaku, Hashimoto, Wataru
Format:	Artikel
Sprache:	eng
Schlagworte:	Alginates - metabolism Bacterial Proteins - chemistry Bacterial Proteins - metabolism Binding Sites Biological Transport Copper - metabolism Crystallography, X-Ray EfeO Glucuronic Acid - metabolism Gram-Negative Bacterial Infections - microbiology Hexuronic Acids - metabolism Iron - metabolism Iron import M75_peptidase Metals - metabolism Models, Molecular Protein Conformation Sphingomonas Sphingomonas - chemistry Sphingomonas - metabolism X-ray crystallography Zinc - metabolism
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