AMP-activated protein kinase protects against anoxia in Drosophila melanogaster

During anoxia, proper energy maintenance is essential in order to maintain neural operation. Starvation activates AMP-activated protein kinase (AMPK), an evolutionarily conserved indicator of cellular energy status, in a cascade which modulates ATP production and consumption. We investigated the rol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Comparative biochemistry and physiology. Part A, Molecular & integrative physiology Molecular & integrative physiology, 2017-12, Vol.214, p.30-39
Hauptverfasser:	Evans, Justin J., Xiao, Chengfeng, Robertson, R. Meldrum
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP-Activated Protein Kinases - antagonists & inhibitors AMP-Activated Protein Kinases - genetics AMP-Activated Protein Kinases - metabolism Animals Animals, Genetically Modified Astrocytes - enzymology Astrocytes - metabolism Astrocytes - pathology Behavior, Animal Brain - enzymology Brain - metabolism Brain - pathology Caloric Restriction - adverse effects Drosophila melanogaster - genetics Drosophila melanogaster - growth & development Drosophila melanogaster - metabolism Drosophila Proteins - antagonists & inhibitors Drosophila Proteins - genetics Drosophila Proteins - metabolism Fat Body - enzymology Fat Body - metabolism Fat Body - pathology Female Gene Expression Regulation, Developmental Hypoxia - metabolism Hypoxia - pathology Hypoxia - veterinary Larva - genetics Larva - growth & development Larva - metabolism Locomotion Male Nerve Tissue Proteins - antagonists & inhibitors Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neuroglia - enzymology Neuroglia - metabolism Neuroglia - pathology Neurons - enzymology Neurons - metabolism Neurons - pathology Neuroprotection Organ Specificity RNA - metabolism RNA Interference
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!