Inflammaging and the Age-Specific Responsiveness to Stretch-Shortening Contractions
With aging, muscle injury from rapid, continuous stretch-shortening contractions (SSC) is prolonged, and maladaptation to moderate-velocity, intermittent SSC is more common. We hypothesize that high baseline levels of inflammatory signaling and oxidative stress may underlie these outcomes, whereas c...
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Veröffentlicht in: | Exercise and sport sciences reviews 2017-10, Vol.45 (4), p.195-200 |
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description | With aging, muscle injury from rapid, continuous stretch-shortening contractions (SSC) is prolonged, and maladaptation to moderate-velocity, intermittent SSC is more common. We hypothesize that high baseline levels of inflammatory signaling and oxidative stress may underlie these outcomes, whereas careful modulation of high-intensity SSC training design resets basal conditions and permits muscle adaptation to SSC. |
doi_str_mv | 10.1249/jes.0000000000000123 |
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source | MEDLINE; Journals@Ovid LWW Legacy Archive; EZB-FREE-00999 freely available EZB journals |
subjects | Adaptation, Physiological Aging - pathology Animals Humans Inflammation - physiopathology Muscle Contraction - physiology Muscle, Skeletal - injuries Muscle, Skeletal - physiopathology Oxidative Stress |
title | Inflammaging and the Age-Specific Responsiveness to Stretch-Shortening Contractions |
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