Elafin Prevents Lipopolysaccharide-induced AP-1 and NF-κB Activation via an Effect on the Ubiquitin-Proteasome Pathway

The serine anti-protease elafin is expressed by monocytes, alveolar macrophages, neutrophils, and at mucosal surfaces and possesses antimicrobial activity. It is also known to reduce lipopolysaccharide-induced neutrophil influx into murine alveoli as well as to abrogate lipopolysaccharide-induced pr...

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Veröffentlicht in:	The Journal of biological chemistry 2006-11, Vol.281 (46), p.34730-34735
Hauptverfasser:	Butler, Marcus W., Robertson, Ian, Greene, Catherine M., O'Neill, Shane J., Taggart, Clifford C., McElvaney, Noel G.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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