The catalytic activity of a recombinant single chain variable fragment nucleic acid-hydrolysing antibody varies with fusion tag and expression host

The antigen-binding properties of single chain Fv antibodies (scFvs) can vary depending on the position and type of fusion tag used, as well as the host cells used for expression. The issue is even more complicated with a catalytic scFv antibody that binds and hydrolyses a specific antigen. Herein,...

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Veröffentlicht in:Archives of biochemistry and biophysics 2017-11, Vol.633, p.110-117
Hauptverfasser: Lee, Joungmin, Kim, Minjae, Seo, Youngsil, Lee, Yeonjin, Park, Hyunjoon, Byun, Sung June, Kwon, Myung-Hee
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Sprache:eng
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