SV2A and SV2C are not vesicular Ca super(2+) transporters but control glucose-evoked granule recruitment

Synaptic vesicle protein 2 (SV2) is expressed in neuroendocrine cells as three homologous isoforms, SV2A, SV2B and SV2C. Ca super(2+)-dependent function in exocytosis has been attributed to SV2A and SV2B, without elucidation of the mechanism. The role of SV2C has not yet been addressed. Here we char...

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Veröffentlicht in:Journal of cell science 2005-12, Vol.118 (23), p.5647-5660
Hauptverfasser: Iezzi, Mariella, Theander, Sten, Janz, Roger, Loze, Chantal, Wollheim, Claes B
Format: Artikel
Sprache:eng
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