Interleukin-8 Promoter Polymorphism Increases the Risk of Atrophic Gastritis and Gastric Cancer in Japan

Host genetic susceptibility may influence gastric carcinogenesis caused by Helicobacter pylori infection. We aimed to clarify the relationship of interleukin (IL)-8 polymorphism with the risk of atrophic gastritis and gastric cancer. We examined IL-8 −251 T > A, IL-1B −511 C > T, and IL-1RN in...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2005-11, Vol.14 (11), p.2487-2493
Hauptverfasser:	TAGUCHI, Ayumu, OHMIYA, Naoki, SHIRAI, Kennosuke, MABUCHI, Nobuyuki, ITOH, Akihiro, HIROOKA, Yoshiki, NIWA, Yasumasa, GOTO, Hidemi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over atrophic gastritis Atrophy Biological and medical sciences Case-Control Studies Female gastric cancer Gastritis - etiology Gastritis - genetics Gastritis - microbiology Gastroenterology. Liver. Pancreas. Abdomen Genetic Predisposition to Disease Genotype Helicobacter Infections - complications Helicobacter pylori Humans Interleukin-8 Interleukin-8 - biosynthesis Interleukin-8 - genetics Japan Male Medical sciences Middle Aged Odds Ratio p53 polymorphism Polymorphism, Genetic Promoter Regions, Genetic Risk Factors Stomach Diseases - genetics Stomach Diseases - pathology Stomach Neoplasms - etiology Stomach Neoplasms - genetics Stomach Neoplasms - microbiology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors Up-Regulation
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