Gap junctional intercellular communication in adipose‐derived stromal/stem cells is cell density‐dependent and positively impacts adipogenic differentiation

Adipose‐derived stromal/stem cells (ASCs) represent a widely used cell source with multi‐lineage differentiation capacity in approaches for tissue engineering and regenerative medicine. Despite the multitude of literature on their differentiation capacity, little is reported about the physiological...

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Veröffentlicht in:	Journal of cellular physiology 2018-04, Vol.233 (4), p.3315-3329
Hauptverfasser:	Wiesner, Miriam, Berberich, Oliver, Hoefner, Christiane, Blunk, Torsten, Bauer‐Kreisel, Petra
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipogenesis adipogenic differentiation Adipose Tissue - cytology adipose‐derived stromal/stem cells (ASC) Cell Communication Cell Count Cell density Cell interactions Cell signaling Communication Connexin 43 connexin 43 (Cx43) Connexin 43 - metabolism Connexins Crosstalk Cytometry Differentiation Flow cytometry gap junction (GJ) gap junctional intercellular communication (GJIC) Gap junctions Gap Junctions - metabolism Gene expression Gene flow Histology Humans Regenerative medicine Stem cells Stem Cells - metabolism Stromal Cells - metabolism Tissue engineering
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