Diagnostic feasibility and safety of CT-guided core biopsy for lung nodules less than or equal to 8 mm: A single-institution experience
Objectives This retrospective study evaluated the diagnostic yield and safety of CT-guided core biopsy of pulmonary nodules ≤8 mm. Methods We determined the diagnostic yield and safety profile of CT-guided lung biopsies for 125 pulmonary nodules ≤8 mm. Pathological diagnoses were made by a combinati...
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| Veröffentlicht in: | European radiology 2018-02, Vol.28 (2), p.796-806 |
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| creator | Chang, Ying-Yueh Chen, Chun-Ku Yeh, Yi-Chen Wu, Mei-Han |
| description | Objectives
This retrospective study evaluated the diagnostic yield and safety of CT-guided core biopsy of pulmonary nodules ≤8 mm.
Methods
We determined the diagnostic yield and safety profile of CT-guided lung biopsies for 125 pulmonary nodules ≤8 mm. Pathological diagnoses were made by a combination of histopathological examination and imprint cytology. Results were compared with biopsy results for 134 pulmonary nodules >8 and ≤10 mm.
Results
Final diagnoses were established in 94 nodules ≤8 mm. The sensitivity, specificity and diagnostic accuracy of CT-guided core biopsy for nodules ≤8 mm were 87.1 % (61/70 nodules), 100 % (24/24) and 90.4 % (85/94), respectively. Diagnostic failure rates were comparable for nodules ≤8 mm and nodules >8 mm and ≤10 mm (9/94, 9.6 % and 7/111, 6.3 %, respectively,
P=
0.385). The rate of tube thoracostomy for nodules ≤8 mm was comparable to that for nodules >8 and ≤10 mm (1.6 % vs. 0.7 %,
P=
0
.
611). Nodules ≤6 mm had a higher non-diagnostic result rate of 15.4 % (6/39) than did nodules >8 and ≤10 mm (3.7 %, 5/134,
P=
0.017).
Conclusions
CT-guided pulmonary biopsy is feasible for lung nodules ≤8 mm, especially those >6 mm, and has an acceptable diagnostic yield and safety profile.
Key Points
•
CT-guided biopsy of lung nodules ≤8 mm has high diagnostic accuracy.
•
Safety profiles are similar between nodules ≤8 mm and 8–10 mm.
•
Nodules ≤6 mm have higher rates of non-diagnostic results in biopsy.
•
Non-subpleural nodules and old age are risk factors for higher grade haemorrhage.
•
Biopsy is feasible for diagnosing nodules >6 and ≤8 mm. |
| doi_str_mv | 10.1007/s00330-017-5027-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1937521846</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1937521846</sourcerecordid><originalsourceid>FETCH-LOGICAL-c438t-74d4131f0616fc57b68a08de70a8cbb4c33ef2ef4035fe28b431b860d27a8a083</originalsourceid><addsrcrecordid>eNp1kU2LFDEQhoMo7rj6A7xIwIuXaOWjO2lvy_gJC17Wc5PurrRZupPZpAM7v8C_bYZZRQQPRQrqqbcCDyEvObzlAPpdBpASGHDNGhCa8Udkx5UUjINRj8kOOmmY7jp1QZ7lfAsAHVf6KbkQxhglhNiRnx-8nUPMmx-pQ5v94Be_HakNE83WYW2jo_sbNhc_4UTHmJAOPh7ykbqY6FLCTEOcyoKZ1sp0-2EDrRO8K3ahW6SGrut7ekWzD_OCzId6bCubj4Hi_QGTxzDic_LE2SXji4f3knz_9PFm_4Vdf_v8dX91zUYlzca0mhSX3EHLWzc2emiNBTOhBmvGYVCjlOgEOgWycSjMoCQfTAuT0PZEykvy5px7SPGuYN761ecRl8UGjCX3vJO6EdyotqKv_0FvY0mh_q5SBlTXcCErxc_UmGLOCV1_SH616dhz6E-W-rOlvlrqT5Z6XndePSSXYcXpz8ZvLRUQZyDXUZgx_XX6v6m_AOjGnTI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1980495123</pqid></control><display><type>article</type><title>Diagnostic feasibility and safety of CT-guided core biopsy for lung nodules less than or equal to 8 mm: A single-institution experience</title><source>MEDLINE</source><source>SpringerLink (Online service)</source><creator>Chang, Ying-Yueh ; Chen, Chun-Ku ; Yeh, Yi-Chen ; Wu, Mei-Han</creator><creatorcontrib>Chang, Ying-Yueh ; Chen, Chun-Ku ; Yeh, Yi-Chen ; Wu, Mei-Han</creatorcontrib><description>Objectives
This retrospective study evaluated the diagnostic yield and safety of CT-guided core biopsy of pulmonary nodules ≤8 mm.
Methods
We determined the diagnostic yield and safety profile of CT-guided lung biopsies for 125 pulmonary nodules ≤8 mm. Pathological diagnoses were made by a combination of histopathological examination and imprint cytology. Results were compared with biopsy results for 134 pulmonary nodules >8 and ≤10 mm.
Results
Final diagnoses were established in 94 nodules ≤8 mm. The sensitivity, specificity and diagnostic accuracy of CT-guided core biopsy for nodules ≤8 mm were 87.1 % (61/70 nodules), 100 % (24/24) and 90.4 % (85/94), respectively. Diagnostic failure rates were comparable for nodules ≤8 mm and nodules >8 mm and ≤10 mm (9/94, 9.6 % and 7/111, 6.3 %, respectively,
P=
0.385). The rate of tube thoracostomy for nodules ≤8 mm was comparable to that for nodules >8 and ≤10 mm (1.6 % vs. 0.7 %,
P=
0
.
611). Nodules ≤6 mm had a higher non-diagnostic result rate of 15.4 % (6/39) than did nodules >8 and ≤10 mm (3.7 %, 5/134,
P=
0.017).
Conclusions
CT-guided pulmonary biopsy is feasible for lung nodules ≤8 mm, especially those >6 mm, and has an acceptable diagnostic yield and safety profile.
Key Points
•
CT-guided biopsy of lung nodules ≤8 mm has high diagnostic accuracy.
•
Safety profiles are similar between nodules ≤8 mm and 8–10 mm.
•
Nodules ≤6 mm have higher rates of non-diagnostic results in biopsy.
•
Non-subpleural nodules and old age are risk factors for higher grade haemorrhage.
•
Biopsy is feasible for diagnosing nodules >6 and ≤8 mm.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-017-5027-1</identifier><identifier>PMID: 28884222</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Accuracy ; Aged ; Biopsy ; Cellular biology ; Chest ; Computed tomography ; Cytology ; Diagnostic Radiology ; Diagnostic systems ; Failure rates ; Feasibility ; Feasibility Studies ; Female ; Hemorrhage ; Humans ; Image-Guided Biopsy - adverse effects ; Image-Guided Biopsy - methods ; Imaging ; Internal Medicine ; Interventional Radiology ; Lung - diagnostic imaging ; Lung - pathology ; Lung cancer ; Lung nodules ; Male ; Medical diagnosis ; Medical screening ; Medicine ; Medicine & Public Health ; Middle Aged ; Multiple Pulmonary Nodules - diagnostic imaging ; Multiple Pulmonary Nodules - pathology ; Neuroradiology ; Nodules ; Pathology ; Quality ; Radiology ; Retrospective Studies ; Risk analysis ; Risk Factors ; Safety ; Sensitivity and Specificity ; Tomography, X-Ray Computed ; Ultrasound</subject><ispartof>European radiology, 2018-02, Vol.28 (2), p.796-806</ispartof><rights>European Society of Radiology 2017</rights><rights>European Radiology is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438t-74d4131f0616fc57b68a08de70a8cbb4c33ef2ef4035fe28b431b860d27a8a083</citedby><cites>FETCH-LOGICAL-c438t-74d4131f0616fc57b68a08de70a8cbb4c33ef2ef4035fe28b431b860d27a8a083</cites><orcidid>0000-0002-8475-6774</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-017-5027-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-017-5027-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28884222$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chang, Ying-Yueh</creatorcontrib><creatorcontrib>Chen, Chun-Ku</creatorcontrib><creatorcontrib>Yeh, Yi-Chen</creatorcontrib><creatorcontrib>Wu, Mei-Han</creatorcontrib><title>Diagnostic feasibility and safety of CT-guided core biopsy for lung nodules less than or equal to 8 mm: A single-institution experience</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives
This retrospective study evaluated the diagnostic yield and safety of CT-guided core biopsy of pulmonary nodules ≤8 mm.
Methods
We determined the diagnostic yield and safety profile of CT-guided lung biopsies for 125 pulmonary nodules ≤8 mm. Pathological diagnoses were made by a combination of histopathological examination and imprint cytology. Results were compared with biopsy results for 134 pulmonary nodules >8 and ≤10 mm.
Results
Final diagnoses were established in 94 nodules ≤8 mm. The sensitivity, specificity and diagnostic accuracy of CT-guided core biopsy for nodules ≤8 mm were 87.1 % (61/70 nodules), 100 % (24/24) and 90.4 % (85/94), respectively. Diagnostic failure rates were comparable for nodules ≤8 mm and nodules >8 mm and ≤10 mm (9/94, 9.6 % and 7/111, 6.3 %, respectively,
P=
0.385). The rate of tube thoracostomy for nodules ≤8 mm was comparable to that for nodules >8 and ≤10 mm (1.6 % vs. 0.7 %,
P=
0
.
611). Nodules ≤6 mm had a higher non-diagnostic result rate of 15.4 % (6/39) than did nodules >8 and ≤10 mm (3.7 %, 5/134,
P=
0.017).
Conclusions
CT-guided pulmonary biopsy is feasible for lung nodules ≤8 mm, especially those >6 mm, and has an acceptable diagnostic yield and safety profile.
Key Points
•
CT-guided biopsy of lung nodules ≤8 mm has high diagnostic accuracy.
•
Safety profiles are similar between nodules ≤8 mm and 8–10 mm.
•
Nodules ≤6 mm have higher rates of non-diagnostic results in biopsy.
•
Non-subpleural nodules and old age are risk factors for higher grade haemorrhage.
•
Biopsy is feasible for diagnosing nodules >6 and ≤8 mm.</description><subject>Accuracy</subject><subject>Aged</subject><subject>Biopsy</subject><subject>Cellular biology</subject><subject>Chest</subject><subject>Computed tomography</subject><subject>Cytology</subject><subject>Diagnostic Radiology</subject><subject>Diagnostic systems</subject><subject>Failure rates</subject><subject>Feasibility</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Hemorrhage</subject><subject>Humans</subject><subject>Image-Guided Biopsy - adverse effects</subject><subject>Image-Guided Biopsy - methods</subject><subject>Imaging</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - pathology</subject><subject>Lung cancer</subject><subject>Lung nodules</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Medical screening</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Multiple Pulmonary Nodules - diagnostic imaging</subject><subject>Multiple Pulmonary Nodules - pathology</subject><subject>Neuroradiology</subject><subject>Nodules</subject><subject>Pathology</subject><subject>Quality</subject><subject>Radiology</subject><subject>Retrospective Studies</subject><subject>Risk analysis</subject><subject>Risk Factors</subject><subject>Safety</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, X-Ray Computed</subject><subject>Ultrasound</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU2LFDEQhoMo7rj6A7xIwIuXaOWjO2lvy_gJC17Wc5PurrRZupPZpAM7v8C_bYZZRQQPRQrqqbcCDyEvObzlAPpdBpASGHDNGhCa8Udkx5UUjINRj8kOOmmY7jp1QZ7lfAsAHVf6KbkQxhglhNiRnx-8nUPMmx-pQ5v94Be_HakNE83WYW2jo_sbNhc_4UTHmJAOPh7ykbqY6FLCTEOcyoKZ1sp0-2EDrRO8K3ahW6SGrut7ekWzD_OCzId6bCubj4Hi_QGTxzDic_LE2SXji4f3knz_9PFm_4Vdf_v8dX91zUYlzca0mhSX3EHLWzc2emiNBTOhBmvGYVCjlOgEOgWycSjMoCQfTAuT0PZEykvy5px7SPGuYN761ecRl8UGjCX3vJO6EdyotqKv_0FvY0mh_q5SBlTXcCErxc_UmGLOCV1_SH616dhz6E-W-rOlvlrqT5Z6XndePSSXYcXpz8ZvLRUQZyDXUZgx_XX6v6m_AOjGnTI</recordid><startdate>20180201</startdate><enddate>20180201</enddate><creator>Chang, Ying-Yueh</creator><creator>Chen, Chun-Ku</creator><creator>Yeh, Yi-Chen</creator><creator>Wu, Mei-Han</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-8475-6774</orcidid></search><sort><creationdate>20180201</creationdate><title>Diagnostic feasibility and safety of CT-guided core biopsy for lung nodules less than or equal to 8 mm: A single-institution experience</title><author>Chang, Ying-Yueh ; Chen, Chun-Ku ; Yeh, Yi-Chen ; Wu, Mei-Han</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-74d4131f0616fc57b68a08de70a8cbb4c33ef2ef4035fe28b431b860d27a8a083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Accuracy</topic><topic>Aged</topic><topic>Biopsy</topic><topic>Cellular biology</topic><topic>Chest</topic><topic>Computed tomography</topic><topic>Cytology</topic><topic>Diagnostic Radiology</topic><topic>Diagnostic systems</topic><topic>Failure rates</topic><topic>Feasibility</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Hemorrhage</topic><topic>Humans</topic><topic>Image-Guided Biopsy - adverse effects</topic><topic>Image-Guided Biopsy - methods</topic><topic>Imaging</topic><topic>Internal Medicine</topic><topic>Interventional Radiology</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - pathology</topic><topic>Lung cancer</topic><topic>Lung nodules</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Medical screening</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Multiple Pulmonary Nodules - diagnostic imaging</topic><topic>Multiple Pulmonary Nodules - pathology</topic><topic>Neuroradiology</topic><topic>Nodules</topic><topic>Pathology</topic><topic>Quality</topic><topic>Radiology</topic><topic>Retrospective Studies</topic><topic>Risk analysis</topic><topic>Risk Factors</topic><topic>Safety</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, X-Ray Computed</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chang, Ying-Yueh</creatorcontrib><creatorcontrib>Chen, Chun-Ku</creatorcontrib><creatorcontrib>Yeh, Yi-Chen</creatorcontrib><creatorcontrib>Wu, Mei-Han</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database (ProQuest)</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest advanced technologies & aerospace journals</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chang, Ying-Yueh</au><au>Chen, Chun-Ku</au><au>Yeh, Yi-Chen</au><au>Wu, Mei-Han</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic feasibility and safety of CT-guided core biopsy for lung nodules less than or equal to 8 mm: A single-institution experience</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2018-02-01</date><risdate>2018</risdate><volume>28</volume><issue>2</issue><spage>796</spage><epage>806</epage><pages>796-806</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives
This retrospective study evaluated the diagnostic yield and safety of CT-guided core biopsy of pulmonary nodules ≤8 mm.
Methods
We determined the diagnostic yield and safety profile of CT-guided lung biopsies for 125 pulmonary nodules ≤8 mm. Pathological diagnoses were made by a combination of histopathological examination and imprint cytology. Results were compared with biopsy results for 134 pulmonary nodules >8 and ≤10 mm.
Results
Final diagnoses were established in 94 nodules ≤8 mm. The sensitivity, specificity and diagnostic accuracy of CT-guided core biopsy for nodules ≤8 mm were 87.1 % (61/70 nodules), 100 % (24/24) and 90.4 % (85/94), respectively. Diagnostic failure rates were comparable for nodules ≤8 mm and nodules >8 mm and ≤10 mm (9/94, 9.6 % and 7/111, 6.3 %, respectively,
P=
0.385). The rate of tube thoracostomy for nodules ≤8 mm was comparable to that for nodules >8 and ≤10 mm (1.6 % vs. 0.7 %,
P=
0
.
611). Nodules ≤6 mm had a higher non-diagnostic result rate of 15.4 % (6/39) than did nodules >8 and ≤10 mm (3.7 %, 5/134,
P=
0.017).
Conclusions
CT-guided pulmonary biopsy is feasible for lung nodules ≤8 mm, especially those >6 mm, and has an acceptable diagnostic yield and safety profile.
Key Points
•
CT-guided biopsy of lung nodules ≤8 mm has high diagnostic accuracy.
•
Safety profiles are similar between nodules ≤8 mm and 8–10 mm.
•
Nodules ≤6 mm have higher rates of non-diagnostic results in biopsy.
•
Non-subpleural nodules and old age are risk factors for higher grade haemorrhage.
•
Biopsy is feasible for diagnosing nodules >6 and ≤8 mm.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>28884222</pmid><doi>10.1007/s00330-017-5027-1</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-8475-6774</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0938-7994 |
| ispartof | European radiology, 2018-02, Vol.28 (2), p.796-806 |
| issn | 0938-7994 1432-1084 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1937521846 |
| source | MEDLINE; SpringerLink (Online service) |
| subjects | Accuracy Aged Biopsy Cellular biology Chest Computed tomography Cytology Diagnostic Radiology Diagnostic systems Failure rates Feasibility Feasibility Studies Female Hemorrhage Humans Image-Guided Biopsy - adverse effects Image-Guided Biopsy - methods Imaging Internal Medicine Interventional Radiology Lung - diagnostic imaging Lung - pathology Lung cancer Lung nodules Male Medical diagnosis Medical screening Medicine Medicine & Public Health Middle Aged Multiple Pulmonary Nodules - diagnostic imaging Multiple Pulmonary Nodules - pathology Neuroradiology Nodules Pathology Quality Radiology Retrospective Studies Risk analysis Risk Factors Safety Sensitivity and Specificity Tomography, X-Ray Computed Ultrasound |
| title | Diagnostic feasibility and safety of CT-guided core biopsy for lung nodules less than or equal to 8 mm: A single-institution experience |
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