Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat

Pilocarpine administration to rats results in status epilepticus (SE) and after a latency period to the occurrence of spontaneous seizures. The model is commonly used to investigate mechanisms of epileptogenesis as well as the antiepileptic effects of novel compounds. Surprisingly, there have been n...

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Veröffentlicht in:	Experimental neurology 2007-06, Vol.205 (2), p.501-505
Hauptverfasser:	Goffin, Karolien, Nissinen, Jari, Van Laere, Koen, Pitkänen, Asla
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Biological and medical sciences Cyclic pattern Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Electroencephalography Epilepsy, Temporal Lobe - chemically induced Epilepsy, Temporal Lobe - physiopathology Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Male Medical sciences Muscarinic Agonists Nervous system (semeiology, syndromes) Neurology Pilocarpine Rats Rats, Wistar Recurrence Seizure clustering Seizures - physiopathology Spontaneous recurrent seizures Status Epilepticus - chemically induced Status Epilepticus - physiopathology Status Epilepticus - psychology
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