A DNA vaccine encoding CCL4/MIP-1β enhances myocarditis in experimental Trypanosoma cruzi infection in rats

Chagas’ disease, caused by Trypanosoma cruzi, is a major cause of cardiovascular disease in Latin America. Exacerbated inflammation disproportional to parasite load characterizes chronic myocardial lesions in chagasic patients. Chemokines and their receptors are expected to account for the renewed i...

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Veröffentlicht in:Microbes and infection 2006-10, Vol.8 (12), p.2745-2755
Hauptverfasser: Roffê, Ester, Souza, Adriano L.S., Caetano, Bráulia C., Machado, Patrícia P., Barcelos, Lucíola S., Russo, Remo C., Santiago, Helton C., Souza, Danielle G., Pinho, Vanessa, Tanowitz, Herbert B., Camargos, Elisabeth R.S., Bruña-Romero, Oscar, Teixeira, Mauro M.
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Sprache:eng
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