Foxp3 super(+)CD25 super(+)CD4 super(+) natural regulatory T cells in dominant self-tolerance and autoimmune disease
Naturally arising CD25 super(+)CD4 super(+) regulatory T (Treg) cells, most of which are produced by the normal thymus as a functionally mature T-cell subpopulation, play key roles in the maintenance of immunologic self-tolerance and negative control of a variety of physiological and pathological im...
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Veröffentlicht in: | Immunological reviews 2006-08, Vol.212 (1), p.8-27 |
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Hauptverfasser: | , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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