Identification of ω‐ or (ω‐1)‐Hydroxylated Medium‐Chain Acylcarnitines as Novel Urinary Biomarkers for CYP3A Activity

Quantitative models of endogenous metabolites are useful in predicting CYP3A‐mediated drug–drug interactions. This study aimed to identify novel predictive markers for the magnitude of CYP3A induction and inhibition in male and female subjects using an untargeted metabolomics approach. Here we repor...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2018-05, Vol.103 (5), p.879-887
Hauptverfasser:	Kim, Bora, Lee, Jieon, Shin, Kwang‐Hee, Lee, SeungHwan, Yu, Kyung‐Sang, Jang, In‐Jin, Cho, Joo‐Youn
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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