Efficacy and safety of posaconazole in hematopoietic stem cell transplantation patients with invasive fungal disease

Invasive fungal disease (IFD) is a significant cause of morbidity and mortality in hematopoietic stem cell transplantation (HSCT) patients. This study reports real-world efficacy and safety of posaconazole (POS) in HSCT recipients with IFD. We performed a retrospective study to investigate the effic...

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Veröffentlicht in:	Future microbiology 2017-11, Vol.12 (15), p.1371-1379
Hauptverfasser:	Zhang, Sudong, He, Yi, Jiang, Erlie, Wei, Jialin, Yang, Donglin, Zhang, Rongli, Zhai, Weihua, Zhang, Guixin, Wang, Zhao, Zhang, Lining, Liu, Li, Han, Mingzhe, Feng, Sizhou
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antifungal agents Antifungal Agents - administration & dosage Antifungal Agents - adverse effects Antigens Cytomegalovirus Cytomegalovirus Infections - etiology Disease Drug dosages Female Fungal diseases Graft vs Host Disease - etiology Graft-versus-host reaction hematopoietic stem cell transplantation Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic stem cells Humans Infections invasive fungal disease Invasive Fungal Infections - complications Invasive Fungal Infections - prevention & control Leukemia Male Middle Aged Morbidity Mortality Multivariate Analysis Neutropenia Neutropenia - etiology Patients Posaconazole Primary Prevention Regression Analysis Response rates Retrospective Studies Safety Statistics Stem cell transplantation Stem cells Steroids - therapeutic use Time Factors Tomography Transplantation Transplantation Conditioning Transplants & implants Treatment Outcome Triazoles - administration & dosage Triazoles - adverse effects
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