Domain Structure and Protein Interactions of the Silent Information Regulator Sir3 Revealed by Screening a Nested Deletion Library of Protein Fragments

Transcriptional silencing in yeast is mediated by the interactions of silent information regulator (Sir) proteins with chromatin and with one another. The stable association of Sir3 with Sir4 is mediated by a C-terminal region of Sir3 that has additional functions including the dimerization of Sir3....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2006-07, Vol.281 (29), p.20107-20119
Hauptverfasser:	King, Daniel A., Hall, Brian E., Iwamoto, Melanie A., Win, Khine Zar, Chang, Ju Fang, Ellenberger, Tom
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Binding Sites Dimerization DNA, Fungal - genetics Gene Silencing Kinetics Oligodeoxyribonucleotides - chemistry Protein Subunits - chemistry Protein Subunits - metabolism Recombinant Proteins - chemistry Recombinant Proteins - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - metabolism Sequence Deletion Silent Information Regulator Proteins, Saccharomyces cerevisiae - chemistry Silent Information Regulator Proteins, Saccharomyces cerevisiae - genetics Silent Information Regulator Proteins, Saccharomyces cerevisiae - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!