A galactomannoglucan derived from Agaricus brasiliensis: Purification, characterization and macrophage activation via MAPK and IκB/NFκB pathways

•A novel galactomannoglucan was extracted from Agaricus brasiliensis.•It exerted significant effect on macrophage proliferation and activation.•It is a potent inducer in activating mitogen-activated protein kinase pathway.•It is involved in inhibitor of nuclear factor-kappa B/nuclear factor-kappa B...

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Veröffentlicht in:	Food chemistry 2018-01, Vol.239, p.603-611
Hauptverfasser:	Zhang, Yanqing, Liu, Danting, Fang, Leilei, Zhao, Xiaotong, Zhou, Aimin, Xie, Junbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricus Agaricus brasiliensis Cyclooxygenase 2 Escherichia coli I-kappa B Proteins Immunoregulation Lipopolysaccharides Macrophage Activation MAPK and IκB/NFκB pathways NF-kappa B Nitric Oxide Nitric Oxide Synthase Type II Polysaccharide RAW264.7 macrophage Signal Transduction
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