Triplex High-Resolution Melting Assay for the Simultaneous Assessment of IFNL3 rs12979860, ABCB11 rs2287622, and RNF7 rs16851720 Genotypes in Chronic Hepatitis C Patients

Chronic hepatitis C (CHC) is a leading cause of liver disease. Despite the improved efficacy of new antivirals, their high costs preclude their adoption in resource-limited settings, where CHC prevalence is highest. We developed a triplex high-resolution melting assay for the simultaneous assessment...

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Veröffentlicht in:	The Journal of molecular diagnostics : JMD 2017-11, Vol.19 (6), p.857-869
Hauptverfasser:	Enache, Elena L., Sin, Anca, Enache, Liviu S., Bancu, Ligia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult ATP Binding Cassette Transporter, Subfamily B, Member 11 - genetics Female Genotype Hepacivirus - genetics Hepacivirus - pathogenicity Hepatitis C, Chronic - diagnosis Hepatitis C, Chronic - genetics Hepatitis C, Chronic - virology Humans Interferons Interleukins - genetics Male Middle Aged Polymorphism, Single Nucleotide - genetics Transition Temperature Ubiquitin-Protein Ligases - genetics
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